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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922003
Molecular formula	C27H31F4N7
IUPAC name	N-(3-fluoro-2-methylphenyl)-6-piperidin-1-yl-2-[4-[3-(trifluoromethyl)pyridin-2-yl]-1,4-diazepan-1-yl]pyrimidin-4-amine
Molecular weight	529.588
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	6.4
Synonyms	BDBM50358662 SCHEMBL10144200
Inchi Key	JQZOIEVXGHBFNL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31F4N7/c1-19-21(28)9-5-10-22(19)33-23-18-24(36-12-3-2-4-13-36)35-26(34-23)38-15-7-14-37(16-17-38)25-20(27(29,30)31)8-6-11-32-25/h5-6,8-11,18H,2-4,7,12-17H2,1H3,(H,33,34,35)
PubChem CID	57394238
ChEMBL	CHEMBL1922003
IUPHAR	N/A
BindingDB	50358662
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157812	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
157811	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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