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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000567024
Molecular formula	C14H9N3S
IUPAC name	(E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile
Molecular weight	251.307
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.0
Synonyms	Cambridge id 5554994 MolPort-000-305-212 2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acrylonitrile cid_5334847 SR-01000046927-1 (E)-2-(1H-benzimidazol-2-yl)-3-(2-thienyl)acrylonitrile AB00088886-01 BAS 00442707 MDVSLHGZTWHJMW-CSKARUKUSA-N (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile SMR000175048 (2E)-2-(1H-Benzimidazol-2-yl)-3-(2-thienyl)-2-propenenitrile # 2-(1H-benzo[d]imidazol-2-yl)-3-(2-thienyl)acrylonitrile HMS2553D06 ST50728509 (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-2-propenenitrile AC1NSIYA BDBM42055 1H-Benzimidazole-2-acetonitrile, .alpha.-(2-thienylmethylene)- CHEMBL116569 SR-01000046927 (2E)-2-benzimidazol-2-yl-3-(2-thienyl)prop-2-enenitrile AKOS000541721 HMS552K09 ZINC4301938 (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-yl-prop-2-enenitrile [ Show all ]
Inchi Key	MDVSLHGZTWHJMW-CSKARUKUSA-N
Inchi ID	InChI=1S/C14H9N3S/c15-9-10(8-11-4-3-7-18-11)14-16-12-5-1-2-6-13(12)17-14/h1-8H,(H,16,17)/b10-8+
PubChem CID	5334847
ChEMBL	CHEMBL116569
IUPHAR	N/A
BindingDB	42055
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
203064	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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