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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000391056
Molecular formula	C20H27ClN2OS
IUPAC name	1-[1-(2-chlorophenyl)-2-oxocyclohexyl]-3-cyclohexyl-1-methylthiourea
Molecular weight	378.959
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.7
Synonyms	HMS2601O20 AKOS034376070 MolPort-005-726-509 1-[1-(2-chlorophenyl)-2-oxidanylidene-cyclohexyl]-3-cyclohexyl-1-methyl-thiourea CHEMBL1427917 Z45754981 473667-85-5 MCULE-3402174536 BDBM42064 Oprea1_594811 1-[1-(2-chlorophenyl)-2-oxocyclohexyl]-3-cyclohexyl-1-methylthiourea cid_4006073 AC1N1J2G 1-[1-(2-chlorophenyl)-2-keto-cyclohexyl]-3-cyclohexyl-1-methyl-thiourea SMR000260093 [ Show all ]
Inchi Key	CBXZCXFSSRYOGA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H27ClN2OS/c1-23(19(25)22-15-9-3-2-4-10-15)20(14-8-7-13-18(20)24)16-11-5-6-12-17(16)21/h5-6,11-12,15H,2-4,7-10,13-14H2,1H3,(H,22,25)
PubChem CID	4006073
ChEMBL	CHEMBL1427917
IUPHAR	N/A
BindingDB	42064
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38335	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387
38336	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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