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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922025
Molecular formula	C28H35FN6O4
IUPAC name	tert-butyl 4-[6-(3-fluoro-4-methoxyanilino)-2-(4-methoxyanilino)pyrimidin-4-yl]-1,4-diazepane-1-carboxylate
Molecular weight	538.624
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50358673 SCHEMBL10144326
Inchi Key	DGAHYYLIRNCMBX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H35FN6O4/c1-28(2,3)39-27(36)35-14-6-13-34(15-16-35)25-18-24(30-20-9-12-23(38-5)22(29)17-20)32-26(33-25)31-19-7-10-21(37-4)11-8-19/h7-12,17-18H,6,13-16H2,1-5H3,(H2,30,31,32,33)
PubChem CID	57401228
ChEMBL	CHEMBL1922025
IUPHAR	N/A
BindingDB	50358673
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59076	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
59075	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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