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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	brefeldin A
Molecular formula	C16H24O4
IUPAC name	(3E,11E)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one
Molecular weight	280.364
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.0
Synonyms	20350-15-6 KQNZDYYTLMIZCT-GFGVWQOPSA-N SMR004703469 4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11a.beta.,12,13,14,14a.alpha.-decahydro-1.beta.,13.alpha.-dihydroxy-6.beta.-methyl- CHEMBL1987060 MolPort-002-227-778 (2E,10E)-7-methyl-12,15-bis(oxidanyl)-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one BCP22305 Cyanein SCHEMBL4967933 4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-, [1R-(1R,2E,6S,10E,11aS,13S,14aR)]- CCG-22194 MLS000534571 STK177306 (2E,10E)-1,13-dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one AC1NSGNA cid_5362868 NSC 56310 1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one BDBM114316 Decumbin SMR000142008 4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-, [1S-(1R,2E,6R,10E,11aR,13R,14aS)]- MLS006011747 (2E,10E)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one AKOS005410728 Cyanaein REGID_for_CID_5362868 [ Show all ]
Inchi Key	KQNZDYYTLMIZCT-GFGVWQOPSA-N
Inchi ID	InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+
PubChem CID	5362868
ChEMBL	CHEMBL1987060
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
175752	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387
175753	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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