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| Name | Prostaglandin E2 receptor EP2 subtype |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Ptger2 |
| Synonym | EP2 receptor PGE receptor EP2 subtype PGE2 receptor EP2 subtype prostaglandin E receptor 2 (subtype EP2), 53kDa Prostanoid EP2 receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 357 |
| Amino acid sequence | MDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFFSLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYVQYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRALRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL |
| UniProt | Q62928 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4909 |
| IUPHAR | 341 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 11428 |  CHEMBL383515 | C24H28ClNO4 | 429.941 | 4 / 2 | 4.4 | Yes |
| 553305 |  AH 6809 | C17H14O5 | 298.294 | 5 / 1 | 3.9 | Yes |
| 18240 |  CHEMBL551951 | C17H35NO5S | 365.529 | 6 / 2 | 3.1 | Yes |
| 19496 |  CHEMBL2037291 | C29H29N3O5S2 | 563.687 | 9 / 2 | 5.1 | No |
| 20028 |  CHEMBL382197 | C28H31NO4S | 477.619 | 5 / 2 | 5.4 | No |
| 23035 |  CHEMBL46395 | C22H30F3NO4 | 429.48 | 7 / 2 | 3.9 | Yes |
| 553382 |  prostaglandin D2 | C20H32O5 | 352.471 | 5 / 3 | 2.6 | Yes |
| 465993 |  CHEMBL3586309 | C24H22N2O2S | 402.512 | 5 / 0 | 4.5 | Yes |
| 34771 |  CHEMBL553468 | C19H31NO4S | 369.52 | 5 / 1 | 3.8 | Yes |
| 42783 |  CHEMBL208080 | C24H28FNO4 | 413.489 | 5 / 2 | 3.8 | Yes |
| 46520 |  CHEMBL2036325 | C27H24ClN3O4S3 | 586.136 | 9 / 2 | 5.6 | No |
| 48933 |  CHEMBL206774 | C27H35NO5 | 453.579 | 5 / 2 | 4.5 | Yes |
| 55843 |  CHEMBL558671 | C21H27NO4S | 389.51 | 5 / 1 | 3.7 | Yes |
| 553584 |  Doproston | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 66399 |  CHEMBL427035 | C24H29NO4 | 395.499 | 4 / 2 | 3.7 | Yes |
| 70662 |  CHEMBL2036319 | C27H28N2O5S2 | 524.65 | 8 / 2 | 4.5 | No |
| 74549 |  CHEMBL208411 | C30H33NO4 | 471.597 | 4 / 2 | 5.4 | No |
| 75977 |  CHEMBL559955 | C21H27NO4S | 389.51 | 5 / 1 | 4.2 | Yes |
| 553678 |  17-phenyl-trinor-PGE2 | C23H30O5 | 386.488 | 5 / 3 | 2.8 | Yes |
| 91017 |  CHEMBL1957436 | C26H25ClN2O4S2 | 529.066 | 7 / 2 | 5.1 | No |
| 97550 |  CHEMBL2037292 | C27H24ClN3O5S2 | 570.075 | 9 / 2 | 5.0 | No |
| 553749 |  alprostadil | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 109605 |  CHEMBL425409 | C22H30N2O4 | 386.492 | 5 / 2 | 2.7 | Yes |
| 114286 |  CHEMBL425950 | C24H31NO4S | 429.575 | 5 / 2 | 4.6 | Yes |
| 553851 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 120942 |  CHEMBL559820 | C22H29NO4S | 403.537 | 5 / 1 | 4.6 | Yes |
| 128215 |  CHEMBL554823 | C20H33NO5S | 399.546 | 6 / 2 | 3.1 | Yes |
| 134351 |  CHEMBL203076 | C21H31NO5 | 377.481 | 5 / 3 | 2.7 | Yes |
| 143351 |  CHEMBL207237 | C22H26FNO4S | 419.511 | 6 / 2 | 3.9 | Yes |
| 147471 |  CHEMBL2036326 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 481146 |  4-(7-(5-Fluoro-1H-indole-1-yl)-9-chloro-2,3,4,5-tetrahydro-1,4-benzooxazepine-4-yl)methylpyridine-2(1H)-one | C23H19ClFN3O2 | 423.872 | 4 / 1 | 3.3 | Yes |
| 148129 |  CHEMBL222715 | C21H29NO4 | 359.466 | 4 / 2 | 3.3 | Yes |
| 160118 |  CHEMBL2037289 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 163521 |  UNII-XO355X0D3B | C23H26F3NO4S | 469.519 | 8 / 2 | 4.7 | Yes |
| 172015 |  CHEMBL549869 | C21H27NO5S | 405.509 | 6 / 1 | 3.5 | Yes |
| 183323 |  CHEMBL2037290 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 184938 |  CHEMBL223151 | C18H31NO4S | 357.509 | 5 / 2 | 2.3 | Yes |
| 185413 |  CHEMBL559561 | C18H29NO5S | 371.492 | 6 / 1 | 3.0 | Yes |
| 187793 |  CHEMBL2036324 | C27H25N3O4S3 | 551.694 | 9 / 2 | 5.0 | No |
| 190961 |  CHEMBL549461 | C19H31NO4S | 369.52 | 5 / 1 | 4.0 | Yes |
| 191415 |  CHEMBL559760 | C22H29NO4S | 403.537 | 5 / 1 | 4.6 | Yes |
| 554266 |  U 46619 | C21H34O4 | 350.499 | 4 / 2 | 3.9 | Yes |
| 203380 |  CHEMBL425243 | C22H26ClNO4S | 435.963 | 5 / 2 | 4.4 | Yes |
| 554315 |  Taprenepag | C24H22N4O5S | 478.523 | 8 / 1 | 2.5 | Yes |
| 221488 |  CHEMBL379746 | C22H26ClNO4S | 435.963 | 5 / 2 | 4.4 | Yes |
| 222879 |  CHEMBL204058 | C21H30ClNO4 | 395.924 | 4 / 2 | 3.6 | Yes |
| 227180 |  CHEMBL562291 | C21H33NO5S | 411.557 | 6 / 1 | 3.7 | Yes |
| 554446 |  Dpt-prostaglandin E1 | C22H30O5 | 374.477 | 5 / 2 | 3.5 | Yes |
| 236185 |  CHEMBL2036320 | C28H30N2O4S2 | 522.678 | 7 / 2 | 5.2 | No |
| 554542 |  butaprost acid | C23H38O5 | 394.552 | 5 / 3 | 3.9 | Yes |
| 257596 |  CHEMBL562411 | C21H35NO5S | 413.573 | 6 / 2 | 3.6 | Yes |
| 261103 |  CHEMBL2036318 | C27H28N2O4S2 | 508.651 | 7 / 2 | 4.9 | No |
| 261629 |  CHEMBL379785 | C28H31NO4S | 477.619 | 5 / 2 | 5.4 | No |
| 262206 |  CHEMBL1957437 | C30H28N2O4S2 | 544.684 | 7 / 2 | 5.7 | No |
| 263816 |  CHEMBL2036323 | C27H25N3O5S2 | 535.633 | 9 / 2 | 4.4 | No |
| 270348 |  CHEMBL2036322 | C28H26N2O5S2 | 534.645 | 8 / 2 | 4.9 | No |
| 554628 |  dinoprost | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
| 274441 |  CHEMBL2036321 | C28H30N2O4S2 | 522.678 | 7 / 2 | 5.2 | No |
| 280144 |  MK-2894 | C25H22F3NO3S | 473.51 | 7 / 2 | 5.9 | No |
| 284888 |  CHEMBL556333 | C22H29NO4S | 403.537 | 5 / 1 | 3.9 | Yes |
| 285345 |  CHEMBL205819 | C23H35NO5 | 405.535 | 5 / 2 | 2.7 | Yes |
| 300231 |  CHEMBL378968 | C22H26FNO4S | 419.511 | 6 / 2 | 3.9 | Yes |
| 310133 |  CHEMBL541516 | C26H30N2O4S | 466.596 | 6 / 1 | 4.8 | Yes |
| 311052 |  CHEMBL562825 | C22H29NO5S | 419.536 | 6 / 1 | 4.4 | Yes |
| 311438 |  CHEMBL381755 | C30H33NO5 | 487.596 | 5 / 2 | 5.3 | No |
| 314227 |  CHEMBL383339 | C24H37NO5 | 419.562 | 5 / 2 | 3.1 | Yes |
| 320083 |  CHEMBL1933722 | C21H24N2O4S2 | 432.553 | 7 / 2 | 3.2 | Yes |
| 321597 |  CHEMBL380839 | C25H28F3NO4 | 463.497 | 7 / 2 | 4.6 | Yes |
| 324812 |  CHEMBL208510 | C22H30F3NO5 | 445.479 | 8 / 2 | 4.2 | Yes |
| 329178 |  CHEMBL556416 | C25H31N3O5S | 485.599 | 7 / 1 | 3.4 | Yes |
| 331613 |  CHEMBL1957435 | C26H26N2O4S2 | 494.624 | 7 / 2 | 4.5 | Yes |
| 335115 |  CHEMBL549530 | C27H30ClNO4S | 500.05 | 5 / 1 | 6.1 | No |
| 350636 |  CHEMBL549663 | C21H27NO5S | 405.509 | 6 / 1 | 3.9 | Yes |
| 358967 |  CHEMBL550619 | C22H29NO4S | 403.537 | 5 / 1 | 4.3 | Yes |
| 361069 |  CHEMBL208399 | C27H35NO4 | 437.58 | 4 / 2 | 4.6 | Yes |
| 362689 |  CHEMBL559623 | C15H31NO5S | 337.475 | 6 / 2 | 2.2 | Yes |
| 376832 |  CHEMBL203780 | C21H31NO4 | 361.482 | 4 / 2 | 3.0 | Yes |
| 376973 |  CHEMBL549870 | C22H29NO4S | 403.537 | 5 / 1 | 4.1 | Yes |
| 378315 |  Evatanepag | C25H28N2O5S | 468.568 | 7 / 1 | 4.2 | Yes |
| 379374 |  CHEMBL559560 | C16H33NO5S | 351.502 | 6 / 2 | 2.5 | Yes |
| 555203 |  19(R)-hydroxy-PGE2 | C20H32O6 | 368.47 | 6 / 4 | 1.3 | Yes |
| 383165 |  CHEMBL541517 | C24H28N2O4S2 | 472.618 | 7 / 1 | 4.9 | Yes |
| 390101 |  Prostaglandin E2 | C20H32O5 | 352.471 | 5 / 3 | 2.8 | Yes |
| 396081 |  CHEMBL208410 | C26H29NO4S | 451.581 | 5 / 2 | 5.0 | Yes |
| 397262 |  CHEMBL42027 | C19H33NO4 | 339.476 | 4 / 2 | 2.9 | Yes |
| 409920 |  CHEMBL382029 | C22H27NO4S | 401.521 | 5 / 2 | 3.8 | Yes |
| 419501 |  CHEMBL559065 | C27H31NO4S | 465.608 | 5 / 1 | 5.5 | No |
| 427947 |  CHEMBL2113220 | C22H33NO4 | 375.509 | 4 / 2 | 3.4 | Yes |
| 427949 |  CHEMBL208407 | C22H33NO4 | 375.509 | 4 / 2 | 3.4 | Yes |
| 436502 |  CHEMBL444798 | C24H28FNO4 | 413.489 | 5 / 2 | 3.8 | Yes |
| 438547 |  CHEMBL550015 | C16H33NO5S | 351.502 | 6 / 2 | 2.4 | Yes |
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