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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	butaprost acid
Molecular formula	C23H38O5
IUPAC name	7-[(1R,2R,3R)-3-hydroxy-2-[(E,4S)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight	394.552
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.9
Synonyms	SR-01000946411-1 butaprost (free acid form) CHEMBL1628262 (1R)-2beta-[(1E,4S)-4-Hydroxy-4-(1-propylcyclobutyl)-1-butenyl]-3alpha-hydroxy-5-oxocyclopentane-1alpha-heptanoic acid HMS3648D13 7-[(1R,2R,3R)-3-hydroxy-2-[(E,4S)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoic acid ZINC13836509 D08MNO SR-01000946411 BDBM50016954 GTPL1892 [ Show all ]
Inchi Key	PAYNQYXOKJDXAV-ZHIWTBQHSA-N
Inchi ID	InChI=1S/C23H38O5/c1-2-13-23(14-8-15-23)21(26)11-7-10-18-17(19(24)16-20(18)25)9-5-3-4-6-12-22(27)28/h7,10,17-18,20-21,25-26H,2-6,8-9,11-16H2,1H3,(H,27,28)/b10-7+/t17-,18-,20-,21+/m1/s1
PubChem CID	25886893
ChEMBL	CHEMBL1628262
IUPHAR	1892
BindingDB	50016954
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
255310	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
554541	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
255308	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
255307	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
554542	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
255306	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
554540	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365
255312	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
554543	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
554539	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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