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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3586309
Molecular formula	C24H22N2O2S
IUPAC name	7-(1-benzothiophen-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Molecular weight	402.512
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50092617 4-(3-Pyridyl)methyl-7-(1-benzothiophene-3-yl)-9-methoxy-2,3,4,5-tetrahydro-1,4-benzooxazepine
Inchi Key	BJCNATUOCUEACR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3
PubChem CID	30897313
ChEMBL	CHEMBL3586309
IUPHAR	N/A
BindingDB	50092617
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465997	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
465993	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
465994	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
465995	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
465996	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
465992	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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