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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Doproston
Molecular formula	C20H34O4
IUPAC name	7-[(1R,2R)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight	338.488
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.2
Synonyms	CHEMBL3246389 LS-125856 UNII-UG6237D2HO 11-deoxyprostaglandin E1 7-[(1R,2R)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid Doprostone Prost-13-en-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)- 11-Deoxy PGE-1 AKOS032429044 HMS3648B09 SR-01000946400-1 11-deoxy-Prostaglandin E1 D0G5MT MolPort-002-528-276 ZINC4082710 9-oxo-15S-hydroxy-13E-prostaenoic acid FA(20:1(OH,Ke,cyclo)) SCHEMBL1056605 11-deoxy Prostaglandin E1 AY-23578 LMFA03010054 UG6237D2HO 11-DeoxyPGE1 37786-00-8 PDSP2_001670 AC1NR1FA GTPL1925 SR-01000946400 11-Deoxy-PGE1 [ Show all ]
Inchi Key	DPNOTBLPQOITGU-LDDQNKHRSA-N
Inchi ID	InChI=1S/C20H34O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,16-18,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1
PubChem CID	5283055
ChEMBL	N/A
IUPHAR	1925
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553581	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
553584	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
553579	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
553582	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365
553580	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
553583	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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