You can:
| Name | Prostaglandin E2 receptor EP4 subtype |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ptger4 |
| Synonym | EP2 EP4 receptor PGE receptor EP4 subtype PGE2 receptor EP4 subtype prostanoid EP4 receptor |
| Disease | N/A for non-human GPCRs |
| Length | 513 |
| Amino acid sequence | MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTSQTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSHREEPASKGNSLQVTFPSETLKLSEKCI |
| UniProt | P32240 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2489 |
| IUPHAR | 343 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3026 |  CHEMBL1929538 | C21H29NO6S | 423.524 | 7 / 2 | 1.7 | Yes |
| 7812 |  CHEMBL1929550 | C23H33NO4S | 419.58 | 5 / 2 | 2.8 | Yes |
| 8329 |  CHEMBL1094419 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 8332 |  CHEMBL596956 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 9981 |  CHEMBL1094160 | C30H33F2NO4 | 509.594 | 6 / 2 | 6.6 | No |
| 13147 |  CHEMBL1929526 | C23H33NO5 | 403.519 | 5 / 2 | 2.2 | Yes |
| 15946 |  CHEMBL2315052 | C24H23Cl2FN2O2 | 461.358 | 4 / 0 | 6.2 | No |
| 17794 |  CHEMBL2315053 | C27H25Cl2FN2O2 | 499.407 | 4 / 1 | 7.0 | No |
| 18598 |  CHEMBL305126 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 19266 |  acrylic acid derivative, 4 | C25H22N2O3 | 398.462 | 4 / 1 | 5.0 | Yes |
| 19500 |  CHEMBL2037291 | C29H29N3O5S2 | 563.687 | 9 / 2 | 5.1 | No |
| 20625 |  CHEMBL186735 | C26H23NO5 | 429.472 | 5 / 1 | 5.0 | Yes |
| 23629 |  CHEMBL595830 | C25H24N2O4 | 416.477 | 5 / 1 | 4.3 | Yes |
| 25482 |  CHEMBL1819607 | C27H28N2O5 | 460.53 | 6 / 1 | 4.4 | Yes |
| 553399 |  ONO-AE2-227 | C27H23NO3 | 409.485 | 3 / 2 | 6.0 | No |
| 30046 |  CHEMBL2315056 | C26H17Cl4FN2O4S | 614.29 | 6 / 1 | 7.6 | No |
| 31707 |  CHEMBL1095117 | C29H31F2NO4 | 495.567 | 6 / 2 | 6.6 | No |
| 553423 |  ONO-AE1-329 | C23H32O6S2 | 468.623 | 8 / 3 | 2.3 | Yes |
| 35048 |  CHEMBL1819611 | C27H28N2O5 | 460.53 | 6 / 2 | 4.5 | Yes |
| 35479 |  CHEMBL303532 | C24H34O6S2 | 482.65 | 8 / 3 | 2.8 | Yes |
| 36794 |  CHEMBL591034 | C25H25NO4 | 403.478 | 4 / 2 | 4.4 | Yes |
| 553432 |  CR6086 | C26H27F3N2O3 | 472.508 | 7 / 2 | 2.6 | Yes |
| 38364 |  CHEMBL1091741 | C31H27F2N3O4S | 575.631 | 7 / 1 | 5.8 | No |
| 40194 |  CHEMBL1929527 | C22H31NO5S | 421.552 | 6 / 2 | 1.6 | Yes |
| 41357 |  indomethacin | C19H16ClNO4 | 357.79 | 4 / 1 | 4.3 | Yes |
| 41636 |  CHEMBL62885 | C24H38O5 | 406.563 | 5 / 3 | 4.1 | Yes |
| 42120 |  CHEMBL364421 | C23H25NO5 | 395.455 | 5 / 1 | 4.9 | Yes |
| 44621 |  CHEMBL1813120 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 46082 |  CHEMBL1929545 | C21H29NO3S | 375.527 | 4 / 2 | 3.1 | Yes |
| 46525 |  CHEMBL2036325 | C27H24ClN3O4S3 | 586.136 | 9 / 2 | 5.6 | No |
| 49036 |  CHEMBL1929539 | C19H25NO4S2 | 395.532 | 6 / 2 | 2.6 | Yes |
| 51160 |  CHEMBL1091743 | C30H26F2N4O4S | 576.619 | 8 / 2 | 5.1 | No |
| 51198 |  CHEMBL595159 | C25H20N2O3 | 396.446 | 4 / 1 | 5.1 | No |
| 52450 |  CHEMBL60555 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 53536 |  CHEMBL1095769 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 54266 |  CHEMBL1094813 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 55825 |  CHEMBL1929528 | C23H32O5S | 420.564 | 6 / 2 | 2.5 | Yes |
| 61110 |  acrylic acid derivative, 9 | C22H22N2O4 | 378.428 | 5 / 1 | 3.6 | Yes |
| 553583 |  Doproston | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 65789 |  11-deoxy Prostaglandin E1 | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 70663 |  CHEMBL2036319 | C27H28N2O5S2 | 524.65 | 8 / 2 | 4.5 | No |
| 73360 |  CHEMBL1813115 | C28H26N2O5 | 470.525 | 6 / 1 | 5.0 | Yes |
| 74489 |  Rivenprost | C24H34O6S | 450.59 | 7 / 2 | 1.8 | Yes |
| 76211 |  CHEMBL1819606 | C26H26N2O5 | 446.503 | 6 / 1 | 4.0 | Yes |
| 76897 |  CHEMBL361098 | C22H23NO5 | 381.428 | 5 / 1 | 4.7 | Yes |
| 77514 |  acrylic acid derivative, 6 | C24H28O5 | 396.483 | 5 / 2 | 5.2 | No |
| 78134 |  CHEMBL1813117 | C28H25ClN2O5 | 504.967 | 6 / 1 | 5.9 | No |
| 79308 |  CHEMBL292717 | C24H34O6S2 | 482.65 | 8 / 3 | 2.9 | Yes |
| 79335 |  CHEMBL1957434 | C22H24ClNO4S | 433.947 | 5 / 2 | 4.0 | Yes |
| 83131 |  17-phenyl-trinor-PGE2 | C23H30O5 | 386.488 | 5 / 3 | 2.8 | Yes |
| 88523 |  CHEMBL62888 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 91016 |  CHEMBL1957436 | C26H25ClN2O4S2 | 529.066 | 7 / 2 | 5.1 | No |
| 94334 |  CHEMBL62868 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 96077 |  CHEMBL1933718 | C24H27NO4 | 393.483 | 4 / 2 | 3.3 | Yes |
| 96939 |  CHEMBL1094814 | C29H34N2O4 | 474.601 | 5 / 2 | 5.3 | No |
| 97555 |  CHEMBL2037292 | C27H24ClN3O5S2 | 570.075 | 9 / 2 | 5.0 | No |
| 98919 |  CHEMBL183933 | C23H25NO4 | 379.456 | 4 / 1 | 5.3 | No |
| 100243 |  15(R)-Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 100253 |  alprostadil | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 107364 |  CHEMBL365829 | C28H25NO5 | 455.51 | 5 / 1 | 5.5 | No |
| 114992 |  acrylic acid derivative, 16 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 115630 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 553847 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 116629 |  UNII-CQ5912425U | C20H14Cl2FNO3 | 406.234 | 5 / 1 | 5.5 | No |
| 116849 |  CHEMBL293242 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 116856 |  CHEMBL294585 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 120655 |  CHEMBL293856 | C22H30O6S2 | 454.596 | 8 / 3 | 2.0 | Yes |
| 122776 |  CHEMBL602337 | C28H31NO4 | 445.559 | 4 / 2 | 5.6 | No |
| 122820 |  CHEMBL182555 | C22H23NO4 | 365.429 | 4 / 1 | 4.6 | Yes |
| 124613 |  CHEMBL2036314 | C28H31NO5S | 493.618 | 6 / 2 | 4.0 | Yes |
| 127541 |  CHEMBL64188 | C19H32O5S | 372.52 | 6 / 3 | 2.7 | Yes |
| 127759 |  CHEMBL62779 | C23H32O6S2 | 468.623 | 8 / 3 | 2.4 | Yes |
| 132796 |  CHEMBL439934 | C24H33FO5 | 420.521 | 6 / 3 | 3.0 | Yes |
| 134266 |  CHEMBL1813118 | C28H25FN2O5 | 488.515 | 7 / 1 | 5.4 | No |
| 136111 |  CHEMBL1929542 | C20H24F3NO4S2 | 463.53 | 9 / 2 | 3.5 | Yes |
| 139557 |  CHEMBL64483 | C22H34O5 | 378.509 | 5 / 3 | 3.0 | Yes |
| 140013 |  CHEMBL1929531 | C21H29NO5S | 407.525 | 6 / 2 | 2.9 | Yes |
| 141642 |  CHEMBL1819608 | C26H26N2O5 | 446.503 | 6 / 2 | 4.2 | Yes |
| 143371 |  CHEMBL64217 | C18H30O5S2 | 390.553 | 7 / 3 | 2.7 | Yes |
| 143429 |  acrylic acid derivative, 12 | C25H22N2O3 | 398.462 | 4 / 1 | 4.7 | Yes |
| 143857 |  CHEMBL64187 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 143925 |  acrylic acid derivative, 17 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 145300 |  CHEMBL64072 | C23H33FO5S | 440.57 | 7 / 3 | 2.8 | Yes |
| 145871 |  SCHEMBL2962411 | C23H21Cl2FN2O4S | 511.389 | 6 / 1 | 5.7 | No |
| 147468 |  CHEMBL2036326 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 148132 |  CHEMBL222715 | C21H29NO4 | 359.466 | 4 / 2 | 3.3 | Yes |
| 148342 |  CHEMBL185277 | C26H31NO5 | 437.536 | 5 / 1 | 6.1 | No |
| 152586 |  CHEMBL1933723 | C21H24N2O4S2 | 432.553 | 7 / 2 | 3.2 | Yes |
| 154144 |  CHEMBL361457 | C26H23NO4 | 413.473 | 4 / 1 | 5.3 | No |
| 154224 |  CHEMBL1933726 | C23H25F3N2O5S2 | 530.577 | 11 / 2 | 3.6 | No |
| 154465 |  CHEMBL1813116 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 158728 |  CHEMBL2036315 | C26H32N2O5S | 484.611 | 7 / 2 | 2.3 | Yes |
| 158750 |  CHEMBL2315050 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.6 | No |
| 158911 |  CHEMBL1929533 | C20H24F3NO5S | 447.469 | 9 / 2 | 2.9 | Yes |
| 160116 |  CHEMBL2037289 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 160674 |  CHEMBL603633 | C24H22N2O4 | 402.45 | 5 / 1 | 4.6 | Yes |
| 163568 |  CHEMBL2036312 | C27H30N2O5S | 494.606 | 7 / 2 | 3.4 | Yes |
| 163601 |  CHEMBL1094155 | C30H34FNO4 | 491.603 | 5 / 2 | 6.5 | No |
| 163606 |  CHEMBL597146 | C30H34FNO4 | 491.603 | 5 / 2 | 6.5 | No |
| 165027 |  CHEMBL365243 | C25H21NO4 | 399.446 | 4 / 1 | 4.9 | Yes |
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