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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP4 subtype
Species	Mus musculus (Mouse)
Gene	Ptger4
Synonym	EP2 EP4 receptor PGE receptor EP4 subtype PGE2 receptor EP4 subtype prostanoid EP4 receptor
Disease	N/A for non-human GPCRs
Length	513
Amino acid sequence	MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTSQTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
UniProt	P32240
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2489
IUPHAR	343
DrugBank	N/A

Ligand

Name	CHEMBL185277
Molecular formula	C26H31NO5
IUPAC name	5-[1-(4-butoxybenzoyl)-5-methoxy-2-methylindol-3-yl]pentanoic acid
Molecular weight	437.536
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50150976 5-[1-(4-Butoxy-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-pentanoic acid
Inchi Key	JDNVFYCHZVXLHI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31NO5/c1-4-5-16-32-20-12-10-19(11-13-20)26(30)27-18(2)22(8-6-7-9-25(28)29)23-17-21(31-3)14-15-24(23)27/h10-15,17H,4-9,16H2,1-3H3,(H,28,29)
PubChem CID	11282034
ChEMBL	CHEMBL185277
IUPHAR	N/A
BindingDB	50150976
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4200.0 nM	PMID15357992	BindingDB,ChEMBL

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