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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2036319
Molecular formula	C27H28N2O5S2
IUPAC name	2-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(4-methoxyphenyl)phenyl]but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Molecular weight	524.65
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50385129 SCHEMBL10210674
Inchi Key	DWLBFFMLIQEQIV-ORMBLBCUSA-N
Inchi ID	InChI=1S/C27H28N2O5S2/c1-34-23-10-5-19(6-11-23)20-4-2-3-18(15-20)16-22(30)9-7-21-8-12-25(31)29(21)13-14-35-27-28-24(17-36-27)26(32)33/h2-7,9-11,15,17,21-22,30H,8,12-14,16H2,1H3,(H,32,33)/b9-7+/t21-,22+/m0/s1
PubChem CID	57894063
ChEMBL	CHEMBL2036319
IUPHAR	N/A
BindingDB	50385129
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70661	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
70662	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
70665	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
70666	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
70663	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
70664	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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