You can:
| Name | Prostaglandin E2 receptor EP1 subtype |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ptger1 |
| Synonym | EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 405 |
| Amino acid sequence | MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLAQVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL |
| UniProt | P35375 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2181 |
| IUPHAR | 340 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3028 |  CHEMBL1929538 | C21H29NO6S | 423.524 | 7 / 2 | 1.7 | Yes |
| 517333 |  SCHEMBL215462 | C26H30N2O5S | 482.595 | 7 / 1 | 5.3 | No |
| 7813 |  CHEMBL1929550 | C23H33NO4S | 419.58 | 5 / 2 | 2.8 | Yes |
| 8330 |  CHEMBL1094419 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 8334 |  CHEMBL596956 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 517363 |  UNII-94W010PZ1Z | C25H28N2O5S2 | 500.628 | 8 / 1 | 5.5 | No |
| 9979 |  CHEMBL1094160 | C30H33F2NO4 | 509.594 | 6 / 2 | 6.6 | No |
| 13144 |  CHEMBL1929526 | C23H33NO5 | 403.519 | 5 / 2 | 2.2 | Yes |
| 15947 |  CHEMBL2315052 | C24H23Cl2FN2O2 | 461.358 | 4 / 0 | 6.2 | No |
| 17796 |  CHEMBL2315053 | C27H25Cl2FN2O2 | 499.407 | 4 / 1 | 7.0 | No |
| 18602 |  CHEMBL305126 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 19267 |  acrylic acid derivative, 4 | C25H22N2O3 | 398.462 | 4 / 1 | 5.0 | Yes |
| 19499 |  CHEMBL2037291 | C29H29N3O5S2 | 563.687 | 9 / 2 | 5.1 | No |
| 20626 |  CHEMBL186735 | C26H23NO5 | 429.472 | 5 / 1 | 5.0 | Yes |
| 23628 |  CHEMBL595830 | C25H24N2O4 | 416.477 | 5 / 1 | 4.3 | Yes |
| 25480 |  CHEMBL1819607 | C27H28N2O5 | 460.53 | 6 / 1 | 4.4 | Yes |
| 30045 |  CHEMBL2315056 | C26H17Cl4FN2O4S | 614.29 | 6 / 1 | 7.6 | No |
| 31710 |  CHEMBL1095117 | C29H31F2NO4 | 495.567 | 6 / 2 | 6.6 | No |
| 35049 |  CHEMBL1819611 | C27H28N2O5 | 460.53 | 6 / 2 | 4.5 | Yes |
| 35480 |  CHEMBL303532 | C24H34O6S2 | 482.65 | 8 / 3 | 2.8 | Yes |
| 36792 |  CHEMBL591034 | C25H25NO4 | 403.478 | 4 / 2 | 4.4 | Yes |
| 38361 |  CHEMBL1091741 | C31H27F2N3O4S | 575.631 | 7 / 1 | 5.8 | No |
| 40196 |  CHEMBL1929527 | C22H31NO5S | 421.552 | 6 / 2 | 1.6 | Yes |
| 41351 |  indomethacin | C19H16ClNO4 | 357.79 | 4 / 1 | 4.3 | Yes |
| 41634 |  CHEMBL62885 | C24H38O5 | 406.563 | 5 / 3 | 4.1 | Yes |
| 42119 |  CHEMBL364421 | C23H25NO5 | 395.455 | 5 / 1 | 4.9 | Yes |
| 44628 |  CHEMBL1813120 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 46085 |  CHEMBL1929545 | C21H29NO3S | 375.527 | 4 / 2 | 3.1 | Yes |
| 46522 |  CHEMBL2036325 | C27H24ClN3O4S3 | 586.136 | 9 / 2 | 5.6 | No |
| 49037 |  CHEMBL1929539 | C19H25NO4S2 | 395.532 | 6 / 2 | 2.6 | Yes |
| 51161 |  CHEMBL1091743 | C30H26F2N4O4S | 576.619 | 8 / 2 | 5.1 | No |
| 51201 |  CHEMBL595159 | C25H20N2O3 | 396.446 | 4 / 1 | 5.1 | No |
| 52447 |  CHEMBL60555 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 53537 |  CHEMBL1095769 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 54267 |  CHEMBL1094813 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 55829 |  CHEMBL1929528 | C23H32O5S | 420.564 | 6 / 2 | 2.5 | Yes |
| 61109 |  acrylic acid derivative, 9 | C22H22N2O4 | 378.428 | 5 / 1 | 3.6 | Yes |
| 65788 |  11-deoxy Prostaglandin E1 | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 70661 |  CHEMBL2036319 | C27H28N2O5S2 | 524.65 | 8 / 2 | 4.5 | No |
| 73356 |  CHEMBL1813115 | C28H26N2O5 | 470.525 | 6 / 1 | 5.0 | Yes |
| 76208 |  CHEMBL1819606 | C26H26N2O5 | 446.503 | 6 / 1 | 4.0 | Yes |
| 76896 |  CHEMBL361098 | C22H23NO5 | 381.428 | 5 / 1 | 4.7 | Yes |
| 77517 |  acrylic acid derivative, 6 | C24H28O5 | 396.483 | 5 / 2 | 5.2 | No |
| 78136 |  CHEMBL1813117 | C28H25ClN2O5 | 504.967 | 6 / 1 | 5.9 | No |
| 79311 |  CHEMBL292717 | C24H34O6S2 | 482.65 | 8 / 3 | 2.9 | Yes |
| 79334 |  CHEMBL1957434 | C22H24ClNO4S | 433.947 | 5 / 2 | 4.0 | Yes |
| 83127 |  17-phenyl-trinor-PGE2 | C23H30O5 | 386.488 | 5 / 3 | 2.8 | Yes |
| 88522 |  CHEMBL62888 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 91019 |  CHEMBL1957436 | C26H25ClN2O4S2 | 529.066 | 7 / 2 | 5.1 | No |
| 94337 |  CHEMBL62868 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 96074 |  CHEMBL1933718 | C24H27NO4 | 393.483 | 4 / 2 | 3.3 | Yes |
| 96940 |  CHEMBL1094814 | C29H34N2O4 | 474.601 | 5 / 2 | 5.3 | No |
| 97552 |  CHEMBL2037292 | C27H24ClN3O5S2 | 570.075 | 9 / 2 | 5.0 | No |
| 98922 |  CHEMBL183933 | C23H25NO4 | 379.456 | 4 / 1 | 5.3 | No |
| 100248 |  15(R)-Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 100252 |  alprostadil | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 107361 |  CHEMBL365829 | C28H25NO5 | 455.51 | 5 / 1 | 5.5 | No |
| 114991 |  acrylic acid derivative, 16 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 115629 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 553854 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 116630 |  UNII-CQ5912425U | C20H14Cl2FNO3 | 406.234 | 5 / 1 | 5.5 | No |
| 116850 |  CHEMBL293242 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 116853 |  CHEMBL294585 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 120654 |  CHEMBL293856 | C22H30O6S2 | 454.596 | 8 / 3 | 2.0 | Yes |
| 122775 |  CHEMBL602337 | C28H31NO4 | 445.559 | 4 / 2 | 5.6 | No |
| 122823 |  CHEMBL182555 | C22H23NO4 | 365.429 | 4 / 1 | 4.6 | Yes |
| 124612 |  CHEMBL2036314 | C28H31NO5S | 493.618 | 6 / 2 | 4.0 | Yes |
| 127544 |  CHEMBL64188 | C19H32O5S | 372.52 | 6 / 3 | 2.7 | Yes |
| 127763 |  CHEMBL62779 | C23H32O6S2 | 468.623 | 8 / 3 | 2.4 | Yes |
| 132797 |  CHEMBL439934 | C24H33FO5 | 420.521 | 6 / 3 | 3.0 | Yes |
| 134270 |  CHEMBL1813118 | C28H25FN2O5 | 488.515 | 7 / 1 | 5.4 | No |
| 136109 |  CHEMBL1929542 | C20H24F3NO4S2 | 463.53 | 9 / 2 | 3.5 | Yes |
| 518030 |  SCHEMBL215536 | C28H32N2O5S | 508.633 | 7 / 1 | 5.4 | No |
| 518037 |  SCHEMBL212682 | C27H31NO6S | 497.606 | 7 / 1 | 5.9 | No |
| 518046 |  ONO 8130 | C25H28N2O5S2 | 500.628 | 8 / 1 | 5.6 | No |
| 139556 |  CHEMBL64483 | C22H34O5 | 378.509 | 5 / 3 | 3.0 | Yes |
| 518052 |  SCHEMBL213839 | C26H31NO6S | 485.595 | 7 / 1 | 5.8 | No |
| 140015 |  CHEMBL1929531 | C21H29NO5S | 407.525 | 6 / 2 | 2.9 | Yes |
| 141644 |  CHEMBL1819608 | C26H26N2O5 | 446.503 | 6 / 2 | 4.2 | Yes |
| 143368 |  CHEMBL64217 | C18H30O5S2 | 390.553 | 7 / 3 | 2.7 | Yes |
| 143426 |  acrylic acid derivative, 12 | C25H22N2O3 | 398.462 | 4 / 1 | 4.7 | Yes |
| 143859 |  CHEMBL64187 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 143922 |  acrylic acid derivative, 17 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 145304 |  CHEMBL64072 | C23H33FO5S | 440.57 | 7 / 3 | 2.8 | Yes |
| 518100 |  SCHEMBL213530 | C23H25ClN6O3S2 | 533.062 | 9 / 1 | 5.2 | No |
| 147472 |  CHEMBL2036326 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 148133 |  CHEMBL222715 | C21H29NO4 | 359.466 | 4 / 2 | 3.3 | Yes |
| 148344 |  CHEMBL185277 | C26H31NO5 | 437.536 | 5 / 1 | 6.1 | No |
| 152589 |  CHEMBL1933723 | C21H24N2O4S2 | 432.553 | 7 / 2 | 3.2 | Yes |
| 154142 |  CHEMBL361457 | C26H23NO4 | 413.473 | 4 / 1 | 5.3 | No |
| 154221 |  CHEMBL1933726 | C23H25F3N2O5S2 | 530.577 | 11 / 2 | 3.6 | No |
| 154463 |  CHEMBL1813116 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 158727 |  CHEMBL2036315 | C26H32N2O5S | 484.611 | 7 / 2 | 2.3 | Yes |
| 158751 |  CHEMBL2315050 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.6 | No |
| 158910 |  CHEMBL1929533 | C20H24F3NO5S | 447.469 | 9 / 2 | 2.9 | Yes |
| 160113 |  CHEMBL2037289 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 160675 |  CHEMBL603633 | C24H22N2O4 | 402.45 | 5 / 1 | 4.6 | Yes |
| 163571 |  CHEMBL2036312 | C27H30N2O5S | 494.606 | 7 / 2 | 3.4 | Yes |
| 163600 |  CHEMBL1094155 | C30H34FNO4 | 491.603 | 5 / 2 | 6.5 | No |
| 163604 |  CHEMBL597146 | C30H34FNO4 | 491.603 | 5 / 2 | 6.5 | No |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417