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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1813118
Molecular formula	C28H25FN2O5
IUPAC name	2-[5-fluoro-2-methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-3-yl]acetic acid
Molecular weight	488.515
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.4
Synonyms	BDBM50350369 SCHEMBL5647327
Inchi Key	IIWBXJIMFARCEB-NRFANRHFSA-N
Inchi ID	InChI=1S/C28H25FN2O5/c1-17-22(14-27(32)33)23-13-19(29)9-12-24(23)31(17)28(34)18-7-10-20(11-8-18)35-16-21-15-30(2)25-5-3-4-6-26(25)36-21/h3-13,21H,14-16H2,1-2H3,(H,32,33)/t21-/m0/s1
PubChem CID	10228100
ChEMBL	CHEMBL1813118
IUPHAR	N/A
BindingDB	50350369
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134269	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
134263	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
134270	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
134267	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
134264	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
134266	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
134265	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
134268	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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