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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Rivenprost
Molecular formula	C24H34O6S
IUPAC name	methyl 4-[2-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]butanoate
Molecular weight	450.59
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.8
Synonyms	AKOS027326542 methyl 4-[2-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]butanoate 4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3-methoxymethyl-phenyl)-but-1-enyl]-5-oxo-cyclopentyl}-ethylsulfanyl)-butyric acid methyl ester CHEMBL303960 ONO-4819 UNII-1WBO45T413 Methyl 4-((2-((1R,2R,3R)-3-hydroxy-2-((1E,3S)-3-hydroxy-4-(3-(methoxymethyl)phenyl)but-1-en-1-yl)-5-oxocyclopentyl)ethyl)sulfanyl)butanoate ONO-AE1-734 1WBO45T413 BDBM50318871 methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(e)-(3s)-3-hydroxy-4-(m-methoxymethylphenyl)1-butenyl]-5-oxocyclopentyl]-5-thiaheptanoate Rivenprost [INN] 4-[2-[(1R)-2beta-[(1E,3S)-3-Hydroxy-4-[3-(methoxymethyl)phenyl]-1-butenyl]-3alpha-hydroxy-5-oxocyclopentane-1alpha-yl]ethylthio]butyric acid methyl ester D0O4XW ONO-4819.CD ZINC3940680 AE1-734 methyl 4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3-(methoxymethyl)phenyl)but-1-enyl)-5-oxocyclopentyl)ethylthio)butanoate ONO4819 256382-08-8 MolPort-027-640-849 SCHEMBL2309978 4-[[2-[(1R)-2beta-[(3S)-3-Hydroxy-4-[3-(methoxymethyl)phenyl]-1-butenyl]-3alpha-hydroxy-5-oxocyclopentane-1alpha-yl]ethyl]thio]butanoic acid methyl ester GTPL1930 ONO-4819CD [ Show all ]
Inchi Key	FBQUXLIJKPWCAO-AZIFJQEOSA-N
Inchi ID	InChI=1S/C24H34O6S/c1-29-16-18-6-3-5-17(13-18)14-19(25)8-9-20-21(23(27)15-22(20)26)10-12-31-11-4-7-24(28)30-2/h3,5-6,8-9,13,19-22,25-26H,4,7,10-12,14-16H2,1-2H3/b9-8+/t19-,20-,21-,22-/m1/s1
PubChem CID	9803828
ChEMBL	CHEMBL303960
IUPHAR	1930
BindingDB	50318871
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553641	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
74488	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
74489	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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