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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ONO-AE2-227
Molecular formula	C27H23NO3
IUPAC name	2-[[2-(2-naphthalen-1-ylpropanoylamino)phenyl]methyl]benzoic acid
Molecular weight	409.485
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	6.0
Synonyms	AC1NSK9N CHEMBL3260772 BDBM50012549 D0I0UI SCHEMBL5351322 2-[[2-(2-naphthalen-1-ylpropanoylamino)phenyl]methyl]benzoic acid GTPL5824 [ Show all ]
Inchi Key	BLJLWFKNTKAUDA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H23NO3/c1-18(22-15-8-12-19-9-2-5-13-23(19)22)26(29)28-25-16-7-4-11-21(25)17-20-10-3-6-14-24(20)27(30)31/h2-16,18H,17H2,1H3,(H,28,29)(H,30,31)
PubChem CID	5311232
ChEMBL	CHEMBL3260772
IUPHAR	5824
BindingDB	50012549
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553398	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
26696	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
553399	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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