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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL427035
Molecular formula	C24H29NO4
IUPAC name	4-[3-[2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin-1-yl]propyl]benzoic acid
Molecular weight	395.499
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.7
Synonyms	4-(3-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin-1-yl)propyl)benzoic acid SCHEMBL4992115 4-{3-[2-(3-Hydroxy-4-phenyl-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-benzoic acid BDBM50181283 DQLDMXGXNPDHDY-UHFFFAOYSA-N 4-{3-[2-(3-Hydroxy-4-phenyl-butyl)-5-oxo-pyrrolidin-yl]-propyl-}benzoic acid [ Show all ]
Inchi Key	DQLDMXGXNPDHDY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29NO4/c26-22(17-19-5-2-1-3-6-19)14-12-21-13-15-23(27)25(21)16-4-7-18-8-10-20(11-9-18)24(28)29/h1-3,5-6,8-11,21-22,26H,4,7,12-17H2,(H,28,29)
PubChem CID	11326896
ChEMBL	CHEMBL427035
IUPHAR	N/A
BindingDB	50181283
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66401	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
66399	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
66400	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
66398	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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