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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-(7-(5-Fluoro-1H-indole-1-yl)-9-chloro-2,3,4,5-tetrahydro-1,4-benzooxazepine-4-yl)methylpyridine-2(1H)-one
Molecular formula	C23H19ClFN3O2
IUPAC name	4-[[9-chloro-7-(5-fluoroindol-1-yl)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methyl]-1H-pyridin-2-one
Molecular weight	423.872
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.3
Synonyms	N/A
Inchi Key	JCMBXRJQNVPHIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)
PubChem CID	56927669
ChEMBL	CHEMBL3586360
IUPHAR	N/A
BindingDB	50092616
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
481148	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
481140	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
481147	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
481143	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
481141	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
481144	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
481146	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
481145	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
481142	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
481149	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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