You can:
| Name | Prostaglandin D2 receptor 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | PTGDR2 |
| Synonym | CD294 prostaglandin D2 receptor 2 PGD2 receptor Gpr44 G-protein coupled receptor 44 [ Show all ] |
| Disease | Asthma; Chronic obstructive pulmonary disease Asthma Allergy Allergic rhinitis Allergic asthma [ Show all ] |
| Length | 395 |
| Amino acid sequence | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS |
| UniProt | Q9Y5Y4 |
| Protein Data Bank | 6d27, 6d26 |
| GPCR-HGmod model | Q9Y5Y4 |
| 3D structure model | This structure is from PDB ID 6d27. |
| BioLiP | BL0428440, BL0428439 |
| Therapeutic Target Database | T61722 |
| ChEMBL | CHEMBL5071 |
| IUPHAR | 339 |
| DrugBank | BE0003561 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 535909 |  SCHEMBL1939501 | C17H15ClN2O5S | 394.826 | 6 / 1 | 3.0 | Yes |
| 667 |  CHEMBL3685873 | C24H27N3O3 | 405.498 | 4 / 2 | 4.0 | Yes |
| 675 |  CHEMBL1917395 | C16H9ClF2O3 | 322.692 | 5 / 1 | 4.3 | Yes |
| 902 |  CHEMBL384979 | C18H12Br2N2O4 | 480.112 | 5 / 1 | 4.2 | Yes |
| 906 |  CHEMBL1914491 | C20H15ClO6S | 418.844 | 6 / 1 | 3.5 | Yes |
| 946 |  SCHEMBL509214 | C23H21F3N2O2 | 414.428 | 6 / 1 | 5.2 | No |
| 1057 |  CHEMBL2387690 | C21H17N3O2 | 343.386 | 4 / 1 | 3.7 | Yes |
| 535944 |  SCHEMBL1940119 | C19H19ClN2O4S | 406.881 | 5 / 1 | 3.0 | Yes |
| 1209 |  CHEMBL409714 | C20H15Cl2FN2O4 | 437.248 | 5 / 1 | 2.5 | Yes |
| 1212 |  CHEMBL260013 | C20H15Cl2FN2O4 | 437.248 | 5 / 1 | 2.5 | Yes |
| 1213 |  Spiro-indolinone analogue, 90 | C20H15Cl2FN2O4 | 437.248 | 5 / 1 | 2.5 | Yes |
| 1223 |  SCHEMBL2463331 | C18H16F2N4O2 | 358.349 | 7 / 2 | 2.9 | Yes |
| 1224 |  SCHEMBL2464762 | C18H16F2N4O2 | 358.349 | 7 / 2 | 2.9 | Yes |
| 517324 |  CHEMBL3916780 | C27H24FNO6 | 477.488 | 7 / 1 | 4.1 | Yes |
| 517325 |  CHEMBL3975186 | C25H21ClFNO4 | 453.894 | 5 / 1 | 5.0 | Yes |
| 1376 |  SCHEMBL507891 | C22H21F3N2O4S | 466.475 | 8 / 1 | 3.7 | Yes |
| 1522 |  CHEMBL1088284 | C25H17F3N2O2 | 434.418 | 7 / 1 | 5.0 | Yes |
| 535960 |  CHEMBL3904360 | C28H26FNO5 | 475.516 | 6 / 1 | 4.1 | Yes |
| 517327 |  CHEMBL3955736 | C30H29F2NO4 | 505.562 | 6 / 1 | 5.6 | No |
| 2178 |  CHEMBL2011457 | C24H20N2O4 | 400.434 | 4 / 1 | 3.8 | Yes |
| 517328 |  CHEMBL3891887 | C31H34FNO4 | 503.614 | 5 / 1 | 6.0 | No |
| 2427 |  CHEMBL3686004 | C23H23BrFN3O3 | 488.357 | 5 / 2 | 4.6 | Yes |
| 3015 |  CHEMBL361311 | C25H24N2O4S | 448.537 | 5 / 2 | 4.4 | Yes |
| 4084 |  CHEMBL2036021 | C17H17N5O | 307.357 | 4 / 1 | 2.5 | Yes |
| 4120 |  CHEMBL585385 | C27H26Cl2N2O7S | 593.472 | 8 / 3 | 5.2 | No |
| 517339 |  CHEMBL3901887 | C28H27F2NO4 | 479.524 | 6 / 1 | 4.8 | Yes |
| 4168 |  CHEMBL1689125 | C23H27ClN2O4 | 430.929 | 5 / 1 | 1.4 | Yes |
| 4173 |  CHEMBL2181755 | C22H23ClFNO4 | 419.877 | 5 / 1 | 4.8 | Yes |
| 517341 |  CHEMBL3927763 | C28H27F2NO4 | 479.524 | 6 / 1 | 4.8 | Yes |
| 4358 |  CHEMBL2048166 | C17H16N2O2S | 312.387 | 4 / 1 | 3.8 | Yes |
| 4448 |  CHEMBL507198 | C24H25FN2O3 | 408.473 | 4 / 2 | 4.6 | Yes |
| 441905 |  CHEMBL3338267 | C27H26N4O2 | 438.531 | 4 / 1 | 5.1 | No |
| 5447 |  CHEMBL3685923 | C25H29N3O3 | 419.525 | 4 / 2 | 4.5 | Yes |
| 5551 |  CHEMBL3685924 | C25H27Cl2N3O3 | 488.409 | 4 / 2 | 5.7 | No |
| 5612 |  CHEMBL2042237 | C23H17ClN4O6 | 480.861 | 7 / 2 | 2.2 | Yes |
| 5793 |  CHEMBL3685907 | C21H29N3O3 | 371.481 | 4 / 2 | 3.5 | Yes |
| 5808 |  CHEMBL3093599 | C31H22N2O4 | 486.527 | 5 / 2 | 5.7 | No |
| 5931 |  CHEMBL2030117 | C16H18Cl2N2O2 | 341.232 | 3 / 1 | 4.2 | Yes |
| 557451 |  BDBM233337 | C31H32ClNO5 | 534.049 | 5 / 2 | 7.3 | No |
| 557452 |  BDBM233338 | C31H32ClNO5 | 534.049 | 5 / 2 | 7.3 | No |
| 6158 |  CHEMBL2204471 | C22H16F3N3O3 | 427.383 | 7 / 1 | 3.4 | Yes |
| 557454 |  SCHEMBL1569723 | C31H24Cl3NO6 | 612.884 | 6 / 2 | 7.7 | No |
| 441950 |  CHEMBL3338278 | C21H17ClN4O2 | 392.843 | 5 / 1 | 3.6 | Yes |
| 6636 |  CHEMBL590399 | C25H20ClNO3S | 449.949 | 5 / 1 | 6.1 | No |
| 7049 |  SCHEMBL508652 | C27H28F3N3O3 | 499.534 | 7 / 2 | 5.6 | No |
| 7088 |  CHEMBL1778623 | C19H20F3NO5S | 431.426 | 9 / 1 | 3.9 | Yes |
| 7289 |  CHEMBL3667616 | C25H17Cl2FO4S | 503.365 | 5 / 1 | 6.8 | No |
| 7380 |  CHEMBL1951555 | C25H24Cl2N2O6S | 551.435 | 7 / 3 | 5.0 | No |
| 7510 |  CHEMBL1689130 | C22H24Cl2N2O4 | 451.344 | 5 / 1 | 1.6 | Yes |
| 8089 |  CHEMBL2181809 | C29H27FN2O3 | 470.544 | 4 / 2 | 5.2 | No |
| 517359 |  CHEMBL3930371 | C21H18Cl2N4O2 | 429.301 | 4 / 2 | 4.6 | Yes |
| 519734 |  CHEMBL3938068 | C26H20F2N2O4 | 462.453 | 6 / 2 | 3.9 | Yes |
| 8500 |  CHEMBL2036031 | C17H16FN5O | 325.347 | 5 / 1 | 2.6 | Yes |
| 8506 |  CHEMBL178595 | C23H25FN2O4S | 444.521 | 6 / 2 | 4.0 | Yes |
| 8676 |  CHEMBL2387687 | C17H17N3O2 | 295.342 | 4 / 1 | 2.4 | Yes |
| 557529 |  SCHEMBL1569751 | C30H24N2O5 | 492.531 | 6 / 2 | 5.3 | No |
| 536233 |  CHEMBL3956812 | C27H27FN2O4 | 462.521 | 6 / 1 | 3.6 | Yes |
| 9609 |  CHEMBL2385112 | C25H21ClN2O4S | 480.963 | 5 / 1 | 4.8 | Yes |
| 557557 |  SCHEMBL1569975 | C28H25ClN2O5 | 504.967 | 6 / 2 | 5.2 | No |
| 442085 |  CHEMBL3338270 | C22H23N5O2 | 389.459 | 5 / 1 | 3.0 | Yes |
| 9835 |  CHEMBL2048171 | C18H16N2O4S | 356.396 | 6 / 1 | 3.3 | Yes |
| 557563 |  SCHEMBL1569620 | C28H25Cl2NO5 | 526.41 | 5 / 2 | 6.2 | No |
| 9954 |  2-Formylphenoxyacetic acid | C9H8O4 | 180.159 | 4 / 1 | 0.8 | Yes |
| 9965 |  CHEMBL2391507 | C21H17N3O3 | 359.385 | 4 / 2 | 3.2 | Yes |
| 536253 |  CHEMBL3948154 | C30H31FN2O4 | 502.586 | 6 / 1 | 1.7 | No |
| 10569 |  CHEMBL3237229 | C21H20F4N2O3 | 424.396 | 7 / 1 | 4.0 | Yes |
| 10570 |  CHEMBL3685835 | C23H20ClN3O4 | 437.88 | 5 / 2 | 4.3 | Yes |
| 10582 |  CHEMBL589502 | C22H16ClNO2S | 393.885 | 4 / 1 | 6.7 | No |
| 517374 |  CHEMBL3890838 | C24H25ClN4O2 | 436.94 | 4 / 1 | 4.8 | Yes |
| 464217 |  CHEMBL3673991 | C22H20FN3O2S | 409.479 | 6 / 1 | 4.6 | Yes |
| 10884 |  CHEMBL3685928 | C35H27N3O3 | 537.619 | 4 / 2 | 6.7 | No |
| 11160 |  CHEMBL1081534 | C26H23F3N2O3 | 468.476 | 6 / 0 | 5.6 | No |
| 11161 |  CHEMBL1081535 | C26H23F3N2O3 | 468.476 | 6 / 0 | 5.6 | No |
| 11200 |  CHEMBL1778505 | C23H24N2O3 | 376.456 | 3 / 1 | 3.0 | Yes |
| 11447 |  CHEMBL2048178 | C18H15BrN2O4S | 435.292 | 6 / 1 | 4.0 | Yes |
| 11601 |  CHEMBL3667613 | C26H18F4O5S | 518.479 | 9 / 1 | 6.7 | No |
| 11863 |  CHEMBL1916699 | C26H24F3NO5 | 487.475 | 8 / 1 | 5.1 | No |
| 12036 |  CHEMBL605763 | C25H15F3N2O2S | 464.462 | 8 / 1 | 5.5 | No |
| 12138 |  CHEMBL3093605 | C24H22N2O5 | 418.449 | 6 / 2 | 2.7 | Yes |
| 12181 |  CHEMBL1917447 | C17H13ClFNO4S | 381.802 | 5 / 1 | 3.6 | Yes |
| 12488 |  CHEMBL3093610 | C22H15N3O4S | 417.439 | 7 / 2 | 3.4 | Yes |
| 557641 |  SCHEMBL1569471 | C31H24Cl3NO5 | 596.885 | 5 / 2 | 7.8 | No |
| 12694 |  CHEMBL2042379 | C21H15ClN4O5S | 470.884 | 7 / 1 | 2.4 | Yes |
| 12742 |  SCHEMBL2444000 | C26H21ClN4O2S | 488.99 | 5 / 1 | 5.0 | Yes |
| 517386 |  CHEMBL3930697 | C25H25FN2O5S | 484.542 | 8 / 1 | 4.2 | Yes |
| 12826 |  CHEMBL2205158 | C27H23N3O3 | 437.499 | 4 / 1 | 4.3 | Yes |
| 517387 |  CHEMBL3930966 | C24H23ClN2O5S | 486.967 | 7 / 1 | 4.9 | Yes |
| 536333 |  CHEMBL3906598 | C24H23ClN2O5S | 486.967 | 7 / 1 | 4.9 | Yes |
| 13483 |  CHEMBL2042378 | C23H17ClN4O5S | 496.922 | 7 / 1 | 2.6 | Yes |
| 13490 |  CHEMBL569772 | C25H24Cl2N2O7S | 567.434 | 8 / 3 | 4.7 | No |
| 13578 |  CHEMBL1778514 | C23H22ClFN2O3 | 428.888 | 4 / 1 | 3.7 | Yes |
| 557656 |  SCHEMBL1569470 | C24H17ClN2O5 | 448.859 | 6 / 2 | 4.2 | Yes |
| 14176 |  CHEMBL1684725 | C20H22N2O5S2 | 434.525 | 7 / 1 | 2.2 | Yes |
| 517390 |  CHEMBL3890284 | C25H22FNO4 | 419.452 | 5 / 1 | 4.3 | Yes |
| 536367 |  CHEMBL3944545 | C31H33FN2O5 | 532.612 | 7 / 1 | 4.4 | No |
| 14695 |  SCHEMBL8511017 | C20H19FN4O3 | 382.395 | 5 / 3 | 2.8 | Yes |
| 14748 |  CHEMBL2204477 | C22H19FN4O3 | 406.417 | 6 / 1 | 2.1 | Yes |
| 464686 |  CHEMBL3674016 | C22H19ClFN3O3 | 427.86 | 6 / 1 | 4.6 | Yes |
| 14766 |  CHEMBL2011450 | C25H21FN2O4 | 432.451 | 6 / 1 | 3.6 | Yes |
| 14791 |  CHEMBL2205150 | C26H21N3O3 | 423.472 | 4 / 1 | 4.5 | Yes |
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