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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1088284
Molecular formula	C25H17F3N2O2
IUPAC name	2-[2-[bis(4-fluorophenyl)methyl]-4-(3-fluorophenyl)pyrimidin-5-yl]acetic acid
Molecular weight	434.418
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50312906 SCHEMBL1226883 2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid
Inchi Key	ACFQRXVIUVXHIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H17F3N2O2/c26-19-8-4-15(5-9-19)23(16-6-10-20(27)11-7-16)25-29-14-18(13-22(31)32)24(30-25)17-2-1-3-21(28)12-17/h1-12,14,23H,13H2,(H,31,32)
PubChem CID	16222207
ChEMBL	CHEMBL1088284
IUPHAR	N/A
BindingDB	50312906
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1520	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
1525	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
1521	Prostaglandin D2 receptor 2	Q6XKD3	Ptgdr2	Rattus norvegicus (Rat)	403
1522	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
1524	Prostaglandin D2 receptor 2	Q9Z2J6	Ptgdr2	Mus musculus (Mouse)	382
1523	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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