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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL382197
Molecular formula	C28H31NO4S
IUPAC name	5-[3-[(2S)-2-[3-hydroxy-4-(3-phenylphenyl)butyl]-5-oxopyrrolidin-1-yl]propyl]thiophene-2-carboxylic acid
Molecular weight	477.619
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.4
Synonyms	BDBM50181290 SCHEMBL4992003 5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-thiophene-2-carboxylic acid
Inchi Key	BCBYBNIDJGIOQL-UXMRNZNESA-N
Inchi ID	InChI=1S/C28H31NO4S/c30-24(19-20-6-4-9-22(18-20)21-7-2-1-3-8-21)13-11-23-12-16-27(31)29(23)17-5-10-25-14-15-26(34-25)28(32)33/h1-4,6-9,14-15,18,23-24,30H,5,10-13,16-17,19H2,(H,32,33)/t23-,24?/m0/s1
PubChem CID	44409910
ChEMBL	CHEMBL382197
IUPHAR	N/A
BindingDB	50181290
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20027	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
20028	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
20029	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
20026	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488

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