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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP2 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger2
Synonym	EP2 receptor PGE receptor EP2 subtype PGE2 receptor EP2 subtype prostaglandin E receptor 2 (subtype EP2), 53kDa Prostanoid EP2 receptor Ptger-ep2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFFSLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYVQYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRALRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL
UniProt	Q62928
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4909
IUPHAR	341
DrugBank	N/A

Ligand

Name	CHEMBL550015
Molecular formula	C16H33NO5S
IUPAC name	7-[(4-hydroxy-6-methylheptyl)-methylsulfonylamino]heptanoic acid
Molecular weight	351.502
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.4
Synonyms	7-(N-(4-hydroxy-6-methylheptyl)methylsulfonamido)heptanoic acid BDBM50293499
Inchi Key	ZVOQGQCKCWWWMA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H33NO5S/c1-14(2)13-15(18)9-8-12-17(23(3,21)22)11-7-5-4-6-10-16(19)20/h14-15,18H,4-13H2,1-3H3,(H,19,20)
PubChem CID	45270403
ChEMBL	CHEMBL550015
IUPHAR	N/A
BindingDB	50293499
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2503.0 nM	PMID19250823	BindingDB,ChEMBL

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