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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Taprenepag
Molecular formula	C24H22N4O5S
IUPAC name	2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetic acid
Molecular weight	478.523
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.5
Synonyms	API0013863 CP-544326;CP544326;CP 544326 GTPL5816 Taprenepag (USAN/INN) 9CD894KUMJ BDBM50016953 D09968 KS-00000TTV Taprenepagum 2-(3-((((4-(1H-pyrazol-1-yl)phenyl)methyl)(pyridin-3-ylsulfonyl)amino) methyl)phenoxy)acetic acid AK547949 CP 544326 DTXSID00226187 SCHEMBL3318549 BCP17228 CP544326 HY-14899 Taprenepag [USAN:INN] Acetic acid, 2-(3-((((4-(1H-pyrazol-1-yl)phenyl)methyl)(3-pyridinylsulfonyl)amino) methyl)phenoxy)- D0Y3LL PF 04217329 UNII-9CD894KUMJ 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetic acid AKOS030632799 CP-544326 EX-A941 752187-80-7 BCP24232 CS-5590 J-690347 Taprenepag(CP-544326) acetic acid, [3-[[[[4-(1H-pyrazol-1-yl)phenyl]methyl](3-pyridinylsulfonyl)amino]methyl]phenoxy]- CHEMBL2107783 DB12623 PF-4217329 ZINC72266311 [ Show all ]
Inchi Key	MFFBXYNKZHTCEY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22N4O5S/c29-24(30)18-33-22-5-1-4-20(14-22)17-27(34(31,32)23-6-2-11-25-15-23)16-19-7-9-21(10-8-19)28-13-3-12-26-28/h1-15H,16-18H2,(H,29,30)
PubChem CID	18376177
ChEMBL	CHEMBL2107783
IUPHAR	5816
BindingDB	50016953
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
203998	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
203997	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
554315	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
204000	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
203999	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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