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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	prostaglandin D2
Molecular formula	C20H32O5
IUPAC name	(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid
Molecular weight	352.471
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.6
Synonyms	5179-EP2281563A1 9S,15S-dihydroxy-11-oxo-5Z,13E-prostadienoate BSPBio_001486 E8965369-341A-46F4-8677-2CEB4F9432BA IDI1_033956 Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9-alpha,13E,15S)- (5Z,13E)-(15S)-9,15-dihydroxy-11-oxoprosta-5,13-dienoate SR-01000946237-1 (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate (5Z,9alpha,13E,15S)-9,15-dihydroxy-11-oxo-prosta-5,13-dien-1-oate 198163-EP2272827A1 5179-EP2295409A1 AKOS032954030 CHEMBL1235252 HMS1361K08 MFCD00077857 Prostaglandin D2, >=95%, synthetic (5z,13e)-(15s)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoic acid [3H]-PGD2 (5Z,13E,15S)-9a,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic acid (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid 5179-EP2272832A1 5179-EP2316459A1 BML1-F05 HMS3402K08 NCGC00161284-03 (5E,13E)-9,15-DIHYDROXY-11-OXOPROSTA-5,13-DIEN-1-OIC ACID SCHEMBL2508829 (5Z,13E)-(15S)-9alpha,15-Dihydroxy-11-oxoprosta-5,13-dienoate [3H]prostaglandin D2 (5Z,9-alpha,13E,15S)-9,15-dihydroxy-11-oxo-Prosta-5,13-dien-1-oate 11-Dehydroprostaglandin F2alpha 198163-EP2270004A1 5179-EP2281813A1 9S,15S-dihydroxy-11-oxo-5Z,13E-prostadienoic acid C00696 GTPL1881 LMFA03010004 prosta-glandin d2 (5Z,13E)-(15S)-9,15-dihydroxy-11-oxoprosta-5,13-dienoic acid UNII-RXY07S6CZ2 (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoic acid (5Z,9alpha,13E,15S)-9,15-dihydroxy-11-oxo-prosta-5,13-dien-1-oic acid 2004AH 5179-EP2301937A1 BDBM21544 D06KBO HMS1791K08 NCGC00161284-01 Prostaglandin D2, cell culture tested (5Z,13E)-(15S)-9a,15-Dihydroxy-11-oxoprosta-5,13-dienoate [3H]11-dehydroprostaglandin F2-alpha (5Z,13E,15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic acid 11-Dehydroprostaglandin F2 alpha 5179-EP2280006A1 5179-EP2316824A1 BRN 2170623 DB02056 HMS3648M03 PGD2 (5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]hept-5-enoic acid SR-01000946237 (5Z,13E)-(15S)-9alpha,15-Dihydroxy-11-oxoprosta-5,13-dienoic acid (5Z,9-alpha,13E,15S)-9,15-dihydroxy-11-oxo-Prosta-5,13-dien-1-oic acid 198163-EP2272825A2 5179-EP2281815A1 AC1L9LZD CHEBI:15555 GTPL1891 LS-125822 (5z,13e)-(15s)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate ZINC85994848 (5Z,13E,15S)-9a,15-dihydroxy-11-oxoprosta-5,13-dien-1-oate (5Z,9alpha,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid 41598-07-6 5179-EP2305640A2 BHMBVRSPMRCCGG-OUTUXVNYSA-N D0H8QQ HMS1989K08 NCGC00161284-02 RXY07S6CZ2 (5Z,13E)-(15S)-9a,15-Dihydroxy-11-oxoprosta-5,13-dienoic acid [3H]PGD2 (5Z,13E,15S)-9alpha,15-Dihydroxy-11-oxoprosta-5,13-dienoate 11-Dehydroprostaglandin F2-alpha [ Show all ]
Inchi Key	BHMBVRSPMRCCGG-OUTUXVNYSA-N
Inchi ID	InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
PubChem CID	448457
ChEMBL	N/A
IUPHAR	1891, 1881
BindingDB	N/A
DrugBank	DB02056
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553373	Prostaglandin D2 receptor	Q9R261	Ptgdr	Rattus norvegicus (Rat)	357
553374	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
553378	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
23865	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
553369	Prostaglandin D2 receptor 2	Q6XKD3	Ptgdr2	Rattus norvegicus (Rat)	403
553375	Prostaglandin D2 receptor 2	Q9Z2J6	Ptgdr2	Mus musculus (Mouse)	382
553370	Prostaglandin E2 receptor EP1 subtype	P70597	Ptger1	Rattus norvegicus (Rat)	405
553377	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
553376	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
553382	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
553368	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365
553380	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
553371	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
553379	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
553372	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
553381	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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