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Name | Prostaglandin E2 receptor EP1 subtype |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Ptger1 |
Synonym | EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 405 |
Amino acid sequence | MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL |
UniProt | P70597 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5068 |
IUPHAR | 340 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
553306 | AH 6809 | C17H14O5 | 298.294 | 5 / 1 | 3.9 | Yes |
20786 | SCHEMBL6118381 | C20H21ClN2O3 | 372.849 | 4 / 1 | 4.5 | Yes |
553370 | prostaglandin D2 | C20H32O5 | 352.471 | 5 / 3 | 2.6 | Yes |
45102 | SCHEMBL6117410 | C20H15ClN2O4 | 382.8 | 5 / 1 | 3.7 | Yes |
50315 | SCHEMBL6118481 | C21H18N2O3S | 378.446 | 5 / 1 | 4.1 | Yes |
54158 | CHEMBL362851 | C23H16ClNO3S | 421.895 | 5 / 1 | 5.8 | No |
65138 | SCHEMBL6118186 | C23H18FNO3 | 375.399 | 4 / 1 | 4.9 | Yes |
80589 | SCHEMBL6118436 | C20H21NO3 | 323.392 | 3 / 1 | 4.3 | Yes |
553679 | 17-phenyl-trinor-PGE2 | C23H30O5 | 386.488 | 5 / 3 | 2.8 | Yes |
100257 | alprostadil | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
109785 | SCHEMBL6117972 | C23H20N2O3 | 372.424 | 4 / 1 | 4.4 | Yes |
111505 | UNII-U73BV4MML7 | C22H19ClNNaO3 | 403.838 | 4 / 0 | N/A | N/A |
553843 | ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
127611 | SCHEMBL6118789 | C20H16N2O3S | 364.419 | 5 / 1 | 3.7 | Yes |
134426 | SCHEMBL6117580 | C23H18FNO3 | 375.399 | 4 / 1 | 4.9 | Yes |
142253 | SCHEMBL6117628 | C23H19NO2 | 341.41 | 2 / 1 | 5.1 | No |
147277 | SCHEMBL6117837 | C21H17NO4 | 347.37 | 4 / 1 | 3.8 | Yes |
156998 | SCHEMBL6117306 | C21H16ClNO4 | 381.812 | 4 / 1 | 4.8 | Yes |
164014 | SCHEMBL6117632 | C22H16F2N2O3 | 394.378 | 6 / 1 | 4.3 | Yes |
554153 | SC 19220 | C16H14ClN3O3 | 331.756 | 3 / 2 | 2.3 | Yes |
173919 | SCHEMBL6117584 | C23H18FNO3 | 375.399 | 4 / 1 | 4.9 | Yes |
192625 | SCHEMBL6117311 | C23H18FNO3 | 375.399 | 4 / 1 | 4.9 | Yes |
554260 | U 46619 | C21H34O4 | 350.499 | 4 / 2 | 3.9 | Yes |
198189 | SCHEMBL6117461 | C22H16ClFN2O3 | 410.829 | 5 / 1 | 4.8 | Yes |
210146 | SCHEMBL6118195 | C22H18N2O3 | 358.397 | 4 / 1 | 4.1 | Yes |
215774 | SCHEMBL6117996 | C22H19NO4 | 361.397 | 4 / 1 | 4.6 | Yes |
217691 | SCHEMBL6118235 | C21H16ClN3O3 | 393.827 | 5 / 1 | 3.6 | Yes |
229071 | SCHEMBL6117454 | C19H14ClNO5 | 371.773 | 5 / 1 | 3.9 | Yes |
554442 | Dpt-prostaglandin E1 | C22H30O5 | 374.477 | 5 / 2 | 3.5 | Yes |
245638 | SCHEMBL6117635 | C23H18FNO3 | 375.399 | 4 / 1 | 4.9 | Yes |
252985 | SCHEMBL6117853 | C22H16F2N2O3 | 394.378 | 6 / 1 | 4.3 | Yes |
263324 | SCHEMBL6118739 | C22H18N2O3 | 358.397 | 4 / 1 | 3.7 | Yes |
554599 | enprostil | C23H28O6 | 400.471 | 6 / 2 | 1.3 | Yes |
554630 | dinoprost | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
280149 | MK-2894 | C25H22F3NO3S | 473.51 | 7 / 2 | 5.9 | No |
280736 | SCHEMBL6118477 | C21H16FNO4 | 365.36 | 5 / 1 | 4.3 | Yes |
306192 | CHEMBL467510 | C22H19ClNO3- | 380.848 | 4 / 0 | 6.6 | No |
307129 | SCHEMBL6117861 | C20H15ClN2O3S | 398.861 | 5 / 1 | 4.4 | Yes |
309014 | SCHEMBL6117314 | C21H16FN3O3 | 377.375 | 6 / 1 | 3.1 | Yes |
336531 | SCHEMBL8762524 | C20H16N2O3S | 364.419 | 5 / 1 | 4.2 | Yes |
554990 | Sulprostone | C23H31NO7S | 465.561 | 7 / 3 | 1.5 | Yes |
378639 | SCHEMBL6117257 | C22H16F2N2O3 | 394.378 | 6 / 1 | 4.3 | Yes |
555249 | Prostaglandin E2 | C20H32O5 | 352.471 | 5 / 3 | 2.8 | Yes |
399503 | SCHEMBL6118263 | C22H17ClN2O3 | 392.839 | 4 / 1 | 4.7 | Yes |
421746 | SCHEMBL6117615 | C22H16F2N2O3 | 394.378 | 6 / 1 | 4.3 | Yes |
436700 | SCHEMBL6117558 | C23H19NO3 | 357.409 | 3 / 1 | 4.8 | Yes |
440801 | SCHEMBL6117939 | C21H17NO3S | 363.431 | 4 / 1 | 4.4 | Yes |
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