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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProt	P70597
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5068
IUPHAR	340
DrugBank	N/A

Ligand

Name	SCHEMBL6117615
Molecular formula	C22H16F2N2O3
IUPAC name	6-[[6-fluoro-2-(4-fluorophenyl)-5-methoxyindol-1-yl]methyl]pyridine-2-carboxylic acid
Molecular weight	394.378
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.3
Synonyms	US8680120, 25-31 CHEMBL3665568 BDBM119474
Inchi Key	YXPWKAMVDKTKQV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H16F2N2O3/c1-29-21-10-14-9-19(13-5-7-15(23)8-6-13)26(20(14)11-17(21)24)12-16-3-2-4-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28)
PubChem CID	69670895
ChEMBL	CHEMBL3665568
IUPHAR	N/A
BindingDB	119474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	33.0 nM	, None	BindingDB,ChEMBL

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