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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProt	P70597
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5068
IUPHAR	340
DrugBank	N/A

Ligand

Name	SCHEMBL6117580
Molecular formula	C23H18FNO3
IUPAC name	3-[[2-(4-fluorophenyl)-5-methoxyindol-1-yl]methyl]benzoic acid
Molecular weight	375.399
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.9
Synonyms	US8680120, 25-19 CHEMBL3665563 BDBM119469
Inchi Key	IJCHDZIPTNKYIN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H18FNO3/c1-28-20-9-10-21-18(12-20)13-22(16-5-7-19(24)8-6-16)25(21)14-15-3-2-4-17(11-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)
PubChem CID	69670882
ChEMBL	CHEMBL3665563
IUPHAR	N/A
BindingDB	119469
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	36.0 nM	, None	BindingDB,ChEMBL

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