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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProt	P70597
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5068
IUPHAR	340
DrugBank	N/A

Ligand

Name	SC 19220
Molecular formula	C16H14ClN3O3
IUPAC name	N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
Molecular weight	331.756
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.3
Synonyms	CAS_4336830 GTPL1922 Lopac-S-3065 NCGC00015943-01 NCGC00261782-01 SMR000326951 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-acetylhydrazide AC1N81PQ HMS3267B11 MFCD02259329 NCGC00015943-04 SR-01000076128-3 BDBM85341 D0OA8M KNURFLJTOUGOOQ-UHFFFAOYSA-N N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide NCGC00025038-02 SC19220 ZINC2392218 19395-87-0 CCG-205174 HMS2231G10 Lopac0_001097 NCGC00015943-02 NSC_4336830 SR-01000076128 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid AKOS024456464 CHEMBL112816 HMS3370E15 MLS000862188 NCGC00015943-05 SC 19220, >=98% (HPLC), solid Tocris-1206 BRD-K52512893-001-03-0 EU-0101097 L024046 N'-acetyl-3-chloro-6H-benzo[b][1,5]benzoxazepine-5-carbohydrazide NCGC00025038-03 SCHEMBL12648484 2-Acetylhydrazide 10(11H)-carboxylic acid CHEBI:92916 HMS3263K16 LP01097 NCGC00015943-03 S 3065 SR-01000076128-2 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxy-(2-acetyl)hydrazide B6633 CTK8G3065 J-012559 MolPort-003-959-528 NCGC00025038-01 SC-19220 Tox21_501097 [ Show all ]
Inchi Key	KNURFLJTOUGOOQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
PubChem CID	4336830
ChEMBL	CHEMBL112816
IUPHAR	1922
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	25118.9 nM	PMID9537820	IUPHAR

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