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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProt	P70597
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5068
IUPHAR	340
DrugBank	N/A

Ligand

Name	SCHEMBL6118436
Molecular formula	C20H21NO3
IUPAC name	3-[(5-methoxy-2-propan-2-ylindol-1-yl)methyl]benzoic acid
Molecular weight	323.392
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.3
Synonyms	US8680120, 9-15 CHEMBL3665549 BDBM119455
Inchi Key	FKLJEPXIZZTAMS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21NO3/c1-13(2)19-11-16-10-17(24-3)7-8-18(16)21(19)12-14-5-4-6-15(9-14)20(22)23/h4-11,13H,12H2,1-3H3,(H,22,23)
PubChem CID	69671115
ChEMBL	CHEMBL3665549
IUPHAR	N/A
BindingDB	119455
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	22.0 nM	, None	BindingDB,ChEMBL

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