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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Prostaglandin E2 receptor EP1 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger1
Synonym	EP1 prostanoid receptor EP1 receptor PGE receptor EP1 subtype PGE2 receptor EP1 subtype prostaglandin E receptor 1 (subtype EP1), 42kDa prostanoid EP1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	405
Amino acid sequence	MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
UniProt	P70597
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5068
IUPHAR	340
DrugBank	N/A

Ligand

Name	SCHEMBL6118477
Molecular formula	C21H16FNO4
IUPAC name	5-[[2-(3-fluorophenyl)-5-methoxyindol-1-yl]methyl]furan-2-carboxylic acid
Molecular weight	365.36
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.3
Synonyms	US8680120, 25-11 CHEMBL3665557 BDBM119463
Inchi Key	QKUJAACEYCIDRJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H16FNO4/c1-26-16-5-7-18-14(10-16)11-19(13-3-2-4-15(22)9-13)23(18)12-17-6-8-20(27-17)21(24)25/h2-11H,12H2,1H3,(H,24,25)
PubChem CID	50907866
ChEMBL	CHEMBL3665557
IUPHAR	N/A
BindingDB	119463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	34.0 nM	, None	BindingDB,ChEMBL

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