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| Name | Free fatty acid receptor 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | FFAR2 |
| Synonym | FFA2R G protein-coupled receptor 43 G-protein coupled receptor 43 GPCR3 GPR43 [ Show all ] |
| Disease | Abortion Diabetes |
| Length | 330 |
| Amino acid sequence | MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE |
| UniProt | O15552 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | O15552 |
| 3D structure model | This predicted structure model is from GPCR-EXP O15552. |
| BioLiP | N/A |
| Therapeutic Target Database | T28213 |
| ChEMBL | CHEMBL5493 |
| IUPHAR | 226 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 390 |  CHEMBL593436 | C14H15ClN2O2 | 278.736 | 3 / 1 | 3.4 | Yes |
| 1383 |  CHEMBL595235 | C13H11ClFN3OS | 311.759 | 5 / 1 | 3.5 | Yes |
| 441741 |  CHEMBL3352998 | C22H21ClN2O2S | 412.932 | 3 / 1 | 4.2 | Yes |
| 8969 |  CHEMBL2315528 | C19H15NO2 | 289.334 | 3 / 1 | 3.4 | Yes |
| 9649 |  CHEMBL593517 | C14H15ClN2OS | 294.797 | 3 / 1 | 4.1 | Yes |
| 9924 |  CHEMBL608129 | C13H15ClN2O2S2 | 330.845 | 5 / 1 | 3.7 | Yes |
| 442252 |  CHEMBL3353531 | C26H27ClN2O4S | 499.022 | 5 / 1 | 4.2 | Yes |
| 18586 |  CHEMBL611647 | C14H15ClN2OS | 294.797 | 3 / 1 | 4.1 | Yes |
| 18587 |  AMG-7703 | C14H15ClN2OS | 294.797 | 3 / 1 | 4.1 | Yes |
| 18588 |  4-CMTB | C14H15ClN2OS | 294.797 | 3 / 1 | 4.1 | Yes |
| 21378 |  CHEMBL593120 | C14H17ClN2OS | 296.813 | 3 / 1 | 3.5 | Yes |
| 21561 |  CHEMBL610740 | C18H16Cl2N2O2 | 363.238 | 3 / 1 | 5.5 | No |
| 557983 |  CHEMBL3353504 | C24H25ClN2O5 | 456.923 | 5 / 1 | 2.4 | Yes |
| 23006 |  CHEMBL610333 | C15H16Cl2N2OS | 343.266 | 3 / 1 | 5.4 | No |
| 442626 |  CHEMBL3353490 | C25H25ClN2O2S | 452.997 | 3 / 0 | 4.6 | Yes |
| 442712 |  CHEMBL3353527 | C28H32N2O5 | 476.573 | 5 / 1 | 3.7 | Yes |
| 27782 |  CHEMBL594746 | C16H16ClFN2O | 306.765 | 3 / 1 | 4.4 | Yes |
| 442941 |  SCHEMBL11310920 | C27H28N4O5 | 488.544 | 6 / 2 | 2.6 | Yes |
| 33376 |  CHEMBL594761 | C12H11ClN2OS | 266.743 | 3 / 1 | 3.3 | Yes |
| 467073 |  CHEMBL3600993 | C20H19NO4 | 337.375 | 5 / 1 | 3.7 | Yes |
| 34130 |  CHEMBL595000 | C16H16ClFN2OS | 338.825 | 4 / 1 | 5.1 | No |
| 36312 |  TAK-875 | C29H32O7S | 524.628 | 7 / 1 | 4.7 | No |
| 443199 |  CHEMBL3353507 | C19H22N2O4S | 374.455 | 5 / 1 | 2.1 | Yes |
| 443218 |  CHEMBL3353464 | C25H31ClN2O3 | 442.984 | 3 / 0 | 3.9 | Yes |
| 43305 |  CHEMBL594745 | C16H17ClN2O | 288.775 | 2 / 1 | 3.9 | Yes |
| 44313 |  CID 135971436 | C14H15ClN2O2S | 310.796 | 3 / 1 | 3.7 | Yes |
| 47256 |  CHEMBL611339 | C14H14Cl2N2OS | 329.239 | 3 / 1 | 5.0 | Yes |
| 443584 |  CHEMBL3352999 | C22H25ClN2O2 | 384.904 | 2 / 1 | 3.9 | Yes |
| 50105 |  CHEMBL594974 | C15H14ClFN2OS | 324.798 | 4 / 1 | 4.5 | Yes |
| 443804 |  CHEMBL3353505 | C23H22ClN3O5 | 455.895 | 6 / 1 | 2.7 | Yes |
| 443872 |  CHEMBL3353533 | C28H28N2O5S | 504.601 | 6 / 1 | 4.0 | No |
| 443888 |  CHEMBL3353465 | C24H22ClN3O2S | 451.969 | 4 / 0 | 4.1 | Yes |
| 443889 |  CHEMBL3353506 | C23H23ClN4O4 | 454.911 | 5 / 1 | 2.7 | Yes |
| 559027 |  CHEMBL3353503 | C26H29ClN2O5 | 484.977 | 5 / 1 | 2.6 | Yes |
| 58886 |  CHEMBL594524 | C15H17ClN2OS | 308.824 | 3 / 1 | 4.5 | Yes |
| 59170 |  GW9508 | C22H21NO3 | 347.414 | 4 / 2 | 4.7 | Yes |
| 553550 |  1-Methylcyclopropane-1-carboxylic acid | C5H8O2 | 100.117 | 2 / 1 | 0.6 | Yes |
| 444144 |  CHEMBL3353467 | C27H33ClN2O4 | 485.021 | 4 / 0 | 4.2 | Yes |
| 444209 |  CHEMBL3353480 | C26H30ClN3O4S2 | 548.113 | 6 / 1 | 3.8 | No |
| 444360 |  CHEMBL3353525 | C26H31ClN2O4 | 470.994 | 4 / 1 | 3.9 | Yes |
| 444476 |  CHEMBL3353488 | C27H27ClN2O2 | 446.975 | 2 / 0 | 4.9 | Yes |
| 72046 |  CHEMBL593435 | C15H16ClN3O | 289.763 | 3 / 1 | 2.9 | Yes |
| 553649 |  butyric acid | C4H8O2 | 88.106 | 2 / 1 | 0.8 | Yes |
| 78615 |  CHEMBL593733 | C15H17ClN2OS | 308.824 | 3 / 0 | 4.2 | Yes |
| 81931 |  CHEMBL594505 | C16H17ClN2O3S | 352.833 | 5 / 1 | 4.2 | Yes |
| 83245 |  CHEMBL2047159 | C29H34O8S | 542.643 | 8 / 2 | N/A | No |
| 84332 |  CHEMBL608130 | C18H20ClNO | 301.814 | 1 / 1 | 4.6 | Yes |
| 445086 |  GSK137647A | C16H19NO3S | 305.392 | 4 / 1 | 3.5 | Yes |
| 85780 |  CHEMBL594597 | C14H15ClN2O2S | 310.796 | 4 / 1 | 2.9 | Yes |
| 87983 |  CHEMBL594740 | C13H10ClFN2OS | 296.744 | 4 / 1 | 3.5 | Yes |
| 445225 |  CHEMBL3353486 | C21H22Cl2N2O2 | 405.319 | 2 / 0 | 4.0 | Yes |
| 445626 |  CHEMBL3353516 | C27H26N2O5S | 490.574 | 6 / 1 | 4.0 | Yes |
| 445725 |  CHEMBL3353483 | C24H23ClN2O4S | 470.968 | 5 / 1 | 3.9 | Yes |
| 106603 |  CHEMBL606629 | C18H17ClF6N2O2S | 474.846 | 10 / 2 | 5.7 | No |
| 110604 |  CHEMBL609870 | C13H13ClN2OS | 280.77 | 3 / 1 | 3.6 | Yes |
| 446111 |  CHEMBL3353469 | C25H30ClN3O3 | 455.983 | 3 / 1 | 3.4 | Yes |
| 112268 |  CHEMBL594838 | C15H17ClN2OS | 308.824 | 4 / 0 | 4.9 | Yes |
| 113375 |  CHEMBL609861 | C15H14ClF3N2OS | 362.795 | 6 / 1 | 5.0 | Yes |
| 114746 |  CHEMBL593344 | C15H16BrClN2OS | 387.72 | 3 / 1 | 5.5 | No |
| 446390 |  CHEMBL3353515 | C27H27N3O4S | 489.59 | 5 / 2 | 3.8 | Yes |
| 446529 |  CHEMBL3353496 | C23H23ClN2O2S | 426.959 | 3 / 0 | 4.3 | Yes |
| 122990 |  CHEMBL594738 | C14H13ClN2OS | 292.781 | 3 / 1 | 3.8 | Yes |
| 446594 |  CHEMBL3353497 | C22H21ClN2O2S | 412.932 | 3 / 0 | 4.7 | Yes |
| 125313 |  CHEMBL594998 | C14H12ClFN2OS | 310.771 | 4 / 1 | 4.3 | Yes |
| 446634 |  CHEMBL3353472 | C25H30ClN3O3 | 455.983 | 3 / 1 | 2.9 | Yes |
| 126580 |  CHEMBL596154 | C15H22ClNO | 267.797 | 1 / 1 | 4.1 | Yes |
| 446851 |  CHEMBL3353528 | C27H32N4O4 | 476.577 | 5 / 2 | 2.9 | Yes |
| 446899 |  CHEMBL3353471 | C26H32ClN3O3 | 470.01 | 3 / 1 | 3.3 | Yes |
| 446917 |  CHEMBL3353519 | C23H23N3O4S | 437.514 | 6 / 1 | 3.0 | Yes |
| 446926 |  CHEMBL3353511 | C24H23ClN2O4S | 470.968 | 5 / 1 | 4.3 | Yes |
| 446980 |  CHEMBL3353524 | C27H31F3N2O4 | 504.55 | 7 / 1 | 4.2 | No |
| 135859 |  CHEMBL594744 | C16H17ClN2O | 288.775 | 2 / 1 | 3.6 | Yes |
| 525478 |  CHEMBL3805888 | C19H16FN3O4S | 401.412 | 8 / 2 | 2.9 | Yes |
| 480122 |  CHEMBL3706689 | C24H23ClN2O5 | 454.907 | 5 / 1 | 3.3 | Yes |
| 447265 |  CHEMBL3353538 | C28H29N3O5 | 487.556 | 5 / 2 | 3.1 | Yes |
| 447284 |  CHEMBL3353536 | C27H27F3N2O5 | 516.517 | 8 / 1 | 3.8 | No |
| 144088 |  CHEMBL594302 | C15H15ClN2OS | 306.808 | 3 / 1 | 4.2 | Yes |
| 447526 |  CHEMBL3353475 | C30H34ClN3O4S | 568.129 | 5 / 0 | 3.8 | No |
| 149916 |  CHEMBL596151 | C13H15ClN2O2S2 | 330.845 | 5 / 1 | 3.7 | Yes |
| 151649 |  CHEMBL594507 | C19H24ClN3O3S2 | 441.989 | 6 / 1 | 4.1 | Yes |
| 447713 |  CHEMBL3353493 | C22H23ClN4O2 | 410.902 | 3 / 0 | 3.2 | Yes |
| 153407 |  CHEMBL608384 | C14H15ClN2O2 | 278.736 | 3 / 1 | 3.5 | Yes |
| 447792 |  CHEMBL3353532 | C28H29N3O4S | 503.617 | 5 / 2 | 3.7 | No |
| 158966 |  CHEMBL609852 | C18H17ClN2OS | 344.857 | 3 / 1 | 5.5 | No |
| 161355 |  CHEMBL594737 | C17H22ClN3OS | 351.893 | 4 / 1 | 4.9 | Yes |
| 448209 |  CHEMBL3353508 | C22H28N2O4S | 416.536 | 5 / 1 | 3.4 | Yes |
| 448354 |  SCHEMBL11318840 | C27H28N4O4S | 504.605 | 6 / 2 | 3.2 | No |
| 550038 |  CHEMBL3963542 | C33H40ClNO4 | 550.136 | 5 / 2 | N/A | No |
| 174510 |  CHEMBL595715 | C15H17ClN2OS | 308.824 | 3 / 1 | 4.5 | Yes |
| 554169 |  ISOBUTYRIC ACID | C4H8O2 | 88.106 | 2 / 1 | 0.8 | Yes |
| 448851 |  CHEMBL3353509 | C24H30N2O4S | 442.574 | 5 / 1 | 3.9 | Yes |
| 485514 |  CHEMBL3601003 | C18H15ClN2O4 | 358.778 | 6 / 1 | 3.7 | Yes |
| 526755 |  CHEMBL3805879 | C18H14FN3O3S | 371.386 | 7 / 2 | 3.1 | Yes |
| 449054 |  CHEMBL3353476 | C26H28ClN3O3S | 498.038 | 4 / 1 | 3.7 | Yes |
| 449223 |  CHEMBL3353512 | C24H23ClN2O4S | 470.968 | 5 / 1 | 4.3 | Yes |
| 449348 |  CHEMBL3353491 | C24H23ClN2O2 | 406.91 | 2 / 0 | 4.6 | Yes |
| 449374 |  CHEMBL3353479 | C25H28ClN3O4S2 | 534.086 | 6 / 1 | 3.4 | No |
| 550348 |  CHEMBL3893207 | C34H42ClNO5 | 580.162 | 6 / 2 | N/A | No |
| 449577 |  CHEMBL3352828 | C19H20Cl2N2O3S | 427.34 | 4 / 0 | 4.0 | Yes |
| 449610 |  CHEMBL3353000 | C23H27ClN2O2 | 398.931 | 2 / 0 | 4.1 | Yes |
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