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Name | Free fatty acid receptor 2 |
---|---|
Species | Homo sapiens (Human) |
Gene | FFAR2 |
Synonym | FFA2R G protein-coupled receptor 43 G-protein coupled receptor 43 GPCR3 GPR43 [ Show all ] |
Disease | Abortion Diabetes |
Length | 330 |
Amino acid sequence | MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE |
UniProt | O15552 |
Protein Data Bank | N/A |
GPCR-HGmod model | O15552 |
3D structure model | This predicted structure model is from GPCR-EXP O15552. |
BioLiP | N/A |
Therapeutic Target Database | T28213 |
ChEMBL | CHEMBL5493 |
IUPHAR | 226 |
DrugBank | N/A |
Name | ISOBUTYRIC ACID |
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Molecular formula | C4H8O2 |
IUPAC name | 2-methylpropanoic acid |
Molecular weight | 88.106 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 1 |
XlogP | 0.8 |
Synonyms | Propionic acid, 2-methyl- 11047-EP2311816A1 HSDB 5228 Tenox IBP-2 Grain Pr 11047-EP2316828A1 [ Show all ] |
Inchi Key | KQNPFQTWMSNSAP-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6) |
PubChem CID | 6590 |
ChEMBL | CHEMBL108778 |
IUPHAR | 1060 |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 158489.0 - 630957.0 nM | PMID12711604 | IUPHAR |
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