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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AMG-7703
Molecular formula	C14H15ClN2OS
IUPAC name	(2S)-2-(4-chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
Molecular weight	294.797
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.1
Synonyms	AC1LGZ5A CHEMBL594671 AMG 7703 SCHEMBL16369642 BDBM50305974 AJ-22441 D07ITP (2S)-2-(4-chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide ZINC405199 AKOS022180360 GTPL5803 (S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide AMG7703 [ Show all ]
Inchi Key	AZYDQCGCBQYFSE-LBPRGKRZSA-N
Inchi ID	InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)/t12-/m0/s1
PubChem CID	854189
ChEMBL	CHEMBL594671
IUPHAR	5803
BindingDB	50305974
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18587	Free fatty acid receptor 2	O15552	FFAR2	Homo sapiens (Human)	330
536449	Free fatty acid receptor 2	Q8VCK6	Ffar2	Mus musculus (Mouse)	330

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