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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Free fatty acid receptor 2
Species	Homo sapiens (Human)
Gene	FFAR2
Synonym	FFA2R G protein-coupled receptor 43 G-protein coupled receptor 43 GPCR3 GPR43 FFA2 receptor [ Show all ]
Disease	Abortion Diabetes
Length	330
Amino acid sequence	MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
UniProt	O15552
Protein Data Bank	N/A
GPCR-HGmod model	O15552
3D structure model	This predicted structure model is from GPCR-EXP O15552.
BioLiP	N/A
Therapeutic Target Database	T28213
ChEMBL	CHEMBL5493
IUPHAR	226
DrugBank	N/A

Ligand

Name	CHEMBL595715
Molecular formula	C15H17ClN2OS
IUPAC name	(2S)-2-(4-chlorophenyl)-3-methyl-N-(4-methyl-1,3-thiazol-2-yl)butanamide
Molecular weight	308.824
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.5
Synonyms	(S)-2-(4-chlorophenyl)-3-methyl-N-(4-methylthiazol-2-yl)butanamide BDBM50305969 ZINC7968945 (2S)-2-(4-chlorophenyl)-3-methyl-N-(4-methyl-1,3-thiazol-2-yl)butanamide AC1PKTEA
Inchi Key	KOXXJBZZVATNHN-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C15H17ClN2OS/c1-9(2)13(11-4-6-12(16)7-5-11)14(19)18-15-17-10(3)8-20-15/h4-9,13H,1-3H3,(H,17,18,19)/t13-/m0/s1
PubChem CID	9095896
ChEMBL	CHEMBL595715
IUPHAR	N/A
BindingDB	50305969
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Efficacy	87.0 %	PMID20005104	ChEMBL
IC50	1400.0 nM	PMID20005104	BindingDB,ChEMBL

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