You can:
| Name | Sphingosine 1-phosphate receptor 4 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | S1PR4 |
| Synonym | S1P4 receptor S1P4 S1P receptor Edg-6 S1P receptor 4 endothelial differentiation, G protein-coupled receptor 6 [ Show all ] |
| Disease | N/A |
| Length | 384 |
| Amino acid sequence | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI |
| UniProt | O95977 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | O95977 |
| 3D structure model | This predicted structure model is from GPCR-EXP O95977. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3230 |
| IUPHAR | 278 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 150 |  CHEMBL325198 | C19H34NO3P | 355.459 | 4 / 3 | 2.0 | Yes |
| 540 |  MLS000761483 | C20H19ClN2O | 338.835 | 3 / 1 | 4.5 | Yes |
| 838 |  SMR000178156 | C18H11N3O4 | 333.303 | 5 / 0 | 3.2 | Yes |
| 1375 |  SMR000023524 | C17H26N2O2 | 290.407 | 3 / 0 | 4.2 | Yes |
| 2171 |  SR-02000000242 | C19H15Cl2NO2 | 360.234 | 2 / 1 | 5.8 | No |
| 3498 |  CHEMBL377828 | C26H29N3O3 | 431.536 | 6 / 2 | 3.0 | Yes |
| 4061 |  4035-38-5 | C19H15ClN2O | 322.792 | 3 / 0 | 4.8 | Yes |
| 4206 |  CHEMBL1779914 | C17H15NO2S | 297.372 | 3 / 1 | 4.3 | Yes |
| 4348 |  CHEMBL537632 | C20H31N3O2 | 345.487 | 4 / 4 | 3.2 | Yes |
| 4389 |  CHEMBL117973 | C18H40NO3P | 349.496 | 4 / 3 | 3.3 | Yes |
| 4634 |  diethyl (4-bromobenzylidene)malonate | C14H15BrO4 | 327.174 | 4 / 0 | 4.0 | Yes |
| 5087 |  CYM50199 | C14H12BrCl2NO2 | 377.059 | 3 / 0 | 5.2 | No |
| 5181 |  2-Amino-N-ethyl-5-nitrobenzenesulfonanilide | C14H15N3O4S | 321.351 | 6 / 1 | 2.7 | Yes |
| 5486 |  CHEMBL224571 | C23H19ClF3NO3S | 481.914 | 8 / 1 | 3.1 | Yes |
| 6837 |  CHEMBL1935689 | C15H13Cl2NO4 | 342.172 | 4 / 0 | 4.6 | Yes |
| 7537 |  SMR000204386 | C12H13NO5 | 251.238 | 5 / 0 | 2.4 | Yes |
| 7682 |  CHEMBL196534 | C25H27N3O3 | 417.509 | 6 / 1 | 2.9 | Yes |
| 10098 |  CHEMBL226612 | C20H34FN2O5P | 432.473 | 7 / 4 | 2.2 | Yes |
| 10698 |  CHEMBL206940 | C21H21ClN2O4 | 400.859 | 6 / 1 | 5.0 | Yes |
| 10999 |  CHEMBL334038 | C19H33N2O5P | 400.456 | 6 / 4 | 1.3 | Yes |
| 12297 |  MLS000094258 | C15H10N4O2 | 278.271 | 4 / 0 | 0.5 | Yes |
| 13213 |  CHEMBL1916399 | C22H15F3N4O5 | 472.38 | 11 / 1 | 3.2 | No |
| 13508 |  CHEMBL224005 | C24H22F3NO3S | 461.499 | 8 / 1 | 2.9 | Yes |
| 13767 |  CHEMBL1933158 | C14H10Cl3NO3 | 346.588 | 4 / 0 | 4.5 | Yes |
| 13991 |  CHEMBL115131 | C19H33NO3S | 355.537 | 4 / 2 | 2.7 | Yes |
| 14368 |  3-[(4-chlorophenyl)methoxy]-6-methyl-2-nitropyridine | C13H11ClN2O3 | 278.692 | 4 / 0 | 3.5 | Yes |
| 14402 |  CHEMBL119562 | C15H34NO3P | 307.415 | 4 / 3 | 1.6 | Yes |
| 15841 |  (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene | C12H22O4S2 | 294.424 | 4 / 0 | 2.1 | Yes |
| 553334 |  phytosphingosine 1-phosphate | C18H40NO6P | 397.493 | 7 / 5 | 1.3 | Yes |
| 17996 |  CHEMBL210301 | C20H21N3O4 | 367.405 | 7 / 1 | 3.6 | Yes |
| 548108 |  CHEMBL3883621 | C24H23NO2S | 389.513 | 4 / 2 | 3.2 | Yes |
| 18956 |  SR-02000000326 | C18H22ClN3O3 | 363.842 | 4 / 1 | 4.0 | Yes |
| 19236 |  CYM5954 | C16H18N2O4 | 302.33 | 5 / 0 | 3.8 | Yes |
| 19284 |  MLS000766163 | C25H30N2O | 374.528 | 3 / 0 | 6.7 | No |
| 19456 |  CHEMBL1935674 | C14H12BrClN2O4 | 387.614 | 5 / 0 | 4.4 | Yes |
| 19539 |  CHEMBL211689 | C21H19F3N2O4 | 420.388 | 9 / 1 | 4.8 | Yes |
| 20039 |  SR-02000000318 | C20H18N4O6 | 410.386 | 8 / 0 | 3.8 | Yes |
| 20106 |  CHEMBL241052 | C21H20N4O4 | 392.415 | 8 / 1 | 3.1 | Yes |
| 442460 |  CHEMBL3359519 | C24H24F3NO4 | 447.454 | 7 / 1 | 4.8 | Yes |
| 21323 |  CHEMBL224599 | C23H19BrF3NO3S | 526.368 | 8 / 1 | 3.2 | No |
| 22667 |  CHEMBL1975200 | C20H30N2O2 | 330.472 | 3 / 0 | 4.9 | Yes |
| 519803 |  CHEMBL3769933 | C21H24ClN5O3S | 461.965 | 8 / 1 | 1.3 | Yes |
| 442566 |  CHEMBL3401388 | C29H34FN3O4 | 507.606 | 6 / 2 | 5.7 | No |
| 23079 |  CHEMBL1824257 | C22H23NO2 | 333.431 | 2 / 1 | 5.6 | No |
| 23274 |  SCHEMBL14338632 | C19H34NO4P | 371.458 | 5 / 4 | 1.0 | Yes |
| 24205 |  MLS000834649 | C22H22N4O4 | 406.442 | 5 / 3 | 2.7 | Yes |
| 26332 |  MLS000062663 | C15H9NO2S3 | 331.422 | 5 / 0 | 3.9 | Yes |
| 26762 |  CHEMBL208838 | C25H25F2N3O3 | 453.49 | 8 / 2 | 2.0 | Yes |
| 27286 |  CHEMBL190529 | C19H29N3O | 315.461 | 3 / 3 | 4.0 | Yes |
| 27831 |  CHEMBL364950 | C20H32N3O3PS | 425.528 | 6 / 4 | 4.8 | Yes |
| 29346 |  CHEMBL224799 | C24H22F3NO3S | 461.499 | 8 / 1 | 2.9 | Yes |
| 29520 |  CHEMBL515603 | C22H23N2O6P | 442.408 | 7 / 4 | -0.5 | Yes |
| 31272 |  3-acetyl-7-hydroxy-2H-chromen-2-one | C11H8O4 | 204.181 | 4 / 1 | 1.4 | Yes |
| 31748 |  CHEMBL183888 | C18H29N3O | 303.45 | 3 / 3 | 4.2 | Yes |
| 31888 |  CYM5953 | C15H15ClN2O5 | 338.744 | 6 / 0 | 3.7 | Yes |
| 32551 |  MLS000107096 | C19H14N2O4 | 334.331 | 5 / 0 | 2.8 | Yes |
| 32890 |  CHEMBL195141 | C23H25N3O3 | 391.471 | 6 / 1 | 2.0 | Yes |
| 34332 |  CHEMBL514302 | C20H27N2O6P | 422.418 | 7 / 4 | -1.0 | Yes |
| 522574 |  CHEMBL3806205 | C22H36NO4P | 409.507 | 5 / 3 | 2.0 | Yes |
| 37383 |  CHEMBL117569 | C21H46NO3P | 391.577 | 4 / 3 | 5.0 | Yes |
| 536973 |  SCHEMBL2192987 | C24H26N4O5S | 482.555 | 9 / 1 | 3.1 | Yes |
| 536977 |  SCHEMBL1875982 | C24H26N4O5S | 482.555 | 9 / 1 | 3.1 | Yes |
| 38696 |  CHEMBL196149 | C23H25N3O3 | 391.471 | 6 / 1 | 1.6 | Yes |
| 39210 |  CHEMBL187692 | C21H44NO2P | 373.562 | 3 / 2 | 4.2 | Yes |
| 43936 |  CHEMBL1975908 | C18H28N2O2 | 304.434 | 3 / 0 | 4.4 | Yes |
| 43968 |  MLS000073782 | C17H16F3N5O3S3 | 491.522 | 12 / 1 | 2.8 | No |
| 44329 |  CHEMBL1086170 | C19H34NO4P | 371.458 | 5 / 3 | 0.9 | Yes |
| 44578 |  CYM50174 | C14H11Cl3N2O4 | 377.602 | 5 / 0 | 4.9 | Yes |
| 45267 |  SR-01000698447 | C23H24ClN3O3 | 425.913 | 4 / 1 | 5.1 | No |
| 45301 |  CHEMBL1779916 | C18H17NO2S | 311.399 | 3 / 1 | 4.6 | Yes |
| 45361 |  SR-02000000239 | C19H16ClNO2 | 325.792 | 2 / 1 | 5.2 | No |
| 46414 |  MLS000533685 | C14H8F3N3O4S2 | 403.35 | 9 / 1 | 4.2 | Yes |
| 47462 |  CHEMBL91283 | C38H66N2O7P2 | 724.901 | 9 / 7 | N/A | No |
| 49054 |  CHEMBL224800 | C24H22F3NO4S | 477.498 | 9 / 1 | 2.5 | Yes |
| 49311 |  CHEMBL227851 | C18H31N2O4P | 370.43 | 5 / 4 | 0.5 | Yes |
| 49334 |  CHEMBL433593 | C20H31F3N3O6P | 497.452 | 11 / 5 | N/A | No |
| 49823 |  SMR000047194 | C16H9N5O3 | 319.28 | 6 / 0 | 0.6 | Yes |
| 51564 |  CHEMBL375488 | C25H24F3NO3S | 475.526 | 8 / 1 | 3.3 | Yes |
| 548509 |  CHEMBL3883972 | C22H19NO2S | 361.459 | 4 / 2 | 2.4 | Yes |
| 53455 |  SR-02000000331 | C22H22ClN3O3 | 411.886 | 4 / 1 | 4.3 | Yes |
| 54205 |  CHEMBL3086532 | C13H16ClFN4O3S | 362.804 | 7 / 1 | 1.7 | Yes |
| 57070 |  MLS000737077 | C18H12N2O2 | 288.306 | 3 / 0 | 4.4 | Yes |
| 59073 |  CHEMBL1077288 | C20H33NO3 | 335.488 | 4 / 2 | 2.3 | Yes |
| 59296 |  5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide | C19H15Cl2NO2 | 360.234 | 2 / 1 | 5.8 | No |
| 59554 |  AC1O2QT2 | C20H16N4O | 328.375 | 3 / 1 | 3.3 | Yes |
| 60415 |  CHEMBL377968 | C23H20F3NO3S | 447.472 | 8 / 2 | 2.4 | Yes |
| 62272 |  CHEMBL247699 | C20H34NO5P | 399.468 | 6 / 4 | 1.1 | Yes |
| 62276 |  CHEMBL393055 | C20H34NO5P | 399.468 | 5 / 3 | 1.0 | Yes |
| 63883 |  CHEMBL194898 | C23H23N3O3 | 389.455 | 6 / 1 | 1.8 | Yes |
| 64303 |  CHEMBL209566 | C21H23N3O3 | 365.433 | 6 / 1 | 4.1 | Yes |
| 64834 |  CHEMBL378300 | C24H27N3O3 | 405.498 | 6 / 2 | 2.1 | Yes |
| 64837 |  CHEMBL378061 | C24H27N3O3 | 405.498 | 6 / 2 | 2.1 | Yes |
| 548656 |  CHEMBL3884862 | C20H22N2O2S | 354.468 | 5 / 3 | 1.2 | Yes |
| 65006 |  MLS000374746 | C20H18Cl2N4O4S | 481.348 | 6 / 0 | 2.5 | Yes |
| 548663 |  CHEMBL3883572 | C24H23NO2S | 389.513 | 4 / 2 | 3.2 | Yes |
| 548673 |  CHEMBL3885415 | C25H23NO2S | 401.524 | 4 / 2 | 6.3 | No |
| 66289 |  MLS000570494 | C21H17BrFN3O2S | 474.348 | 6 / 1 | 4.4 | Yes |
| 66380 |  FTY720P | C20H36NO5P | 401.484 | 6 / 4 | 1.1 | Yes |
| 66929 |  2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone | C12H8Cl2O4 | 287.092 | 4 / 0 | 3.1 | Yes |
| 69598 |  Sphingosine 1-phosphate | C18H38NO5P | 379.478 | 6 / 4 | 1.9 | Yes |
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