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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224005
Molecular formula	C24H22F3NO3S
IUPAC name	1-[[3-methyl-4-[[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Molecular weight	461.499
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50158334 SCHEMBL13678349 1-(3-methyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Inchi Key	ASTHITQJQQXIDF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22F3NO3S/c1-15-9-16(11-28-12-18(13-28)23(29)30)7-8-21(15)31-14-19-10-20(17-5-3-2-4-6-17)22(32-19)24(25,26)27/h2-10,18H,11-14H2,1H3,(H,29,30)
PubChem CID	10288527
ChEMBL	CHEMBL224005
IUPHAR	N/A
BindingDB	50158334
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13505	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
13507	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
13506	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
13508	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
13504	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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