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| Name | Sphingosine 1-phosphate receptor 5 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | S1PR5 |
| Synonym | Sphingosine 1-phosphate receptor Edg-8 S1P5 S1P receptor Edg-8 S1P5 receptor S1P receptor 5 [ Show all ] |
| Disease | Multiple scierosis |
| Length | 398 |
| Amino acid sequence | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD |
| UniProt | Q9H228 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | Q9H228 |
| 3D structure model | This predicted structure model is from GPCR-EXP Q9H228. |
| BioLiP | N/A |
| Therapeutic Target Database | T50089 |
| ChEMBL | CHEMBL2274 |
| IUPHAR | 279 |
| DrugBank | BE0002432 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2172 |  SR-02000000242 | C19H15Cl2NO2 | 360.234 | 2 / 1 | 5.8 | No |
| 3501 |  CHEMBL377828 | C26H29N3O3 | 431.536 | 6 / 2 | 3.0 | Yes |
| 4347 |  CHEMBL537632 | C20H31N3O2 | 345.487 | 4 / 4 | 3.2 | Yes |
| 5084 |  CYM50199 | C14H12BrCl2NO2 | 377.059 | 3 / 0 | 5.2 | No |
| 5485 |  CHEMBL224571 | C23H19ClF3NO3S | 481.914 | 8 / 1 | 3.1 | Yes |
| 441924 |  CHEMBL211407 | C21H21ClN2O4 | 400.859 | 6 / 1 | 4.4 | Yes |
| 7683 |  CHEMBL196534 | C25H27N3O3 | 417.509 | 6 / 1 | 2.9 | Yes |
| 10101 |  CHEMBL226612 | C20H34FN2O5P | 432.473 | 7 / 4 | 2.2 | Yes |
| 10694 |  CHEMBL206940 | C21H21ClN2O4 | 400.859 | 6 / 1 | 5.0 | Yes |
| 11002 |  CHEMBL334038 | C19H33N2O5P | 400.456 | 6 / 4 | 1.3 | Yes |
| 521799 |  CHEMBL3739440 | C20H31NO3 | 333.472 | 4 / 1 | 2.7 | Yes |
| 13210 |  CHEMBL1916399 | C22H15F3N4O5 | 472.38 | 11 / 1 | 3.2 | No |
| 13504 |  CHEMBL224005 | C24H22F3NO3S | 461.499 | 8 / 1 | 2.9 | Yes |
| 17994 |  CHEMBL210301 | C20H21N3O4 | 367.405 | 7 / 1 | 3.6 | Yes |
| 548107 |  CHEMBL3883621 | C24H23NO2S | 389.513 | 4 / 2 | 3.2 | Yes |
| 19542 |  CHEMBL211689 | C21H19F3N2O4 | 420.388 | 9 / 1 | 4.8 | Yes |
| 20108 |  CHEMBL241052 | C21H20N4O4 | 392.415 | 8 / 1 | 3.1 | Yes |
| 442458 |  CHEMBL3359519 | C24H24F3NO4 | 447.454 | 7 / 1 | 4.8 | Yes |
| 21031 |  CHEMBL324358 | C15H33N2O5P | 352.412 | 6 / 4 | 0.2 | Yes |
| 21321 |  CHEMBL224599 | C23H19BrF3NO3S | 526.368 | 8 / 1 | 3.2 | No |
| 519800 |  CHEMBL3769933 | C21H24ClN5O3S | 461.965 | 8 / 1 | 1.3 | Yes |
| 442562 |  CHEMBL3401388 | C29H34FN3O4 | 507.606 | 6 / 2 | 5.7 | No |
| 23016 |  CHEMBL1081654 | C18H22N4O2 | 326.4 | 5 / 3 | 3.5 | Yes |
| 522256 |  SCHEMBL3042662 | C17H15Cl2NO2 | 336.212 | 3 / 1 | 1.7 | Yes |
| 26761 |  CHEMBL208838 | C25H25F2N3O3 | 453.49 | 8 / 2 | 2.0 | Yes |
| 27287 |  CHEMBL190529 | C19H29N3O | 315.461 | 3 / 3 | 4.0 | Yes |
| 27833 |  CHEMBL364950 | C20H32N3O3PS | 425.528 | 6 / 4 | 4.8 | Yes |
| 522405 |  SCHEMBL3042200 | C19H17ClF3NO3 | 399.794 | 7 / 1 | 1.7 | Yes |
| 29343 |  CHEMBL224799 | C24H22F3NO3S | 461.499 | 8 / 1 | 2.9 | Yes |
| 29518 |  CHEMBL515603 | C22H23N2O6P | 442.408 | 7 / 4 | -0.5 | Yes |
| 32889 |  CHEMBL195141 | C23H25N3O3 | 391.471 | 6 / 1 | 2.0 | Yes |
| 522542 |  SCHEMBL3044904 | C19H21NO3 | 311.381 | 4 / 1 | 0.6 | Yes |
| 33612 |  CHEMBL423691 | C19H38F3N2O7P | 494.489 | 11 / 5 | N/A | No |
| 33615 |  CHEMBL332472 | C19H38F3N2O7P | 494.489 | 11 / 5 | N/A | No |
| 34329 |  CHEMBL514302 | C20H27N2O6P | 422.418 | 7 / 4 | -1.0 | Yes |
| 522573 |  CHEMBL3806205 | C22H36NO4P | 409.507 | 5 / 3 | 2.0 | Yes |
| 536972 |  SCHEMBL2192987 | C24H26N4O5S | 482.555 | 9 / 1 | 3.1 | Yes |
| 536975 |  SCHEMBL1875982 | C24H26N4O5S | 482.555 | 9 / 1 | 3.1 | Yes |
| 38698 |  CHEMBL196149 | C23H25N3O3 | 391.471 | 6 / 1 | 1.6 | Yes |
| 39211 |  CHEMBL187692 | C21H44NO2P | 373.562 | 3 / 2 | 4.2 | Yes |
| 44327 |  CHEMBL1086170 | C19H34NO4P | 371.458 | 5 / 3 | 0.9 | Yes |
| 44580 |  CYM50174 | C14H11Cl3N2O4 | 377.602 | 5 / 0 | 4.9 | Yes |
| 45300 |  CHEMBL1779916 | C18H17NO2S | 311.399 | 3 / 1 | 4.6 | Yes |
| 45364 |  SR-02000000239 | C19H16ClNO2 | 325.792 | 2 / 1 | 5.2 | No |
| 555658 |  SCHEMBL15909397 | C22H21FN2O4 | 396.418 | 7 / 1 | 0.7 | Yes |
| 522879 |  SCHEMBL3047198 | C18H25NO3 | 303.402 | 4 / 1 | 0.9 | Yes |
| 522963 |  SCHEMBL3037318 | C18H25NO3 | 303.402 | 4 / 1 | 0.7 | Yes |
| 49053 |  CHEMBL224800 | C24H22F3NO4S | 477.498 | 9 / 1 | 2.5 | Yes |
| 49310 |  CHEMBL227851 | C18H31N2O4P | 370.43 | 5 / 4 | 0.5 | Yes |
| 49335 |  CHEMBL433593 | C20H31F3N3O6P | 497.452 | 11 / 5 | N/A | No |
| 51565 |  CHEMBL375488 | C25H24F3NO3S | 475.526 | 8 / 1 | 3.3 | Yes |
| 548508 |  CHEMBL3883972 | C22H19NO2S | 361.459 | 4 / 2 | 2.4 | Yes |
| 54207 |  CHEMBL3086532 | C13H16ClFN4O3S | 362.804 | 7 / 1 | 1.7 | Yes |
| 523145 |  Kinome_2429 | C19H17ClF3NO3 | 399.794 | 7 / 1 | 1.8 | Yes |
| 55965 |  CHEMBL115505 | C17H37N2O6P | 396.465 | 7 / 4 | 1.3 | Yes |
| 523178 |  SCHEMBL3037819 | C18H16Cl2FNO3 | 384.228 | 5 / 1 | 1.6 | Yes |
| 59297 |  5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide | C19H15Cl2NO2 | 360.234 | 2 / 1 | 5.8 | No |
| 60416 |  CHEMBL377968 | C23H20F3NO3S | 447.472 | 8 / 2 | 2.4 | Yes |
| 523304 |  SCHEMBL3041361 | C19H27NO3 | 317.429 | 4 / 1 | 1.3 | Yes |
| 62271 |  CHEMBL247699 | C20H34NO5P | 399.468 | 6 / 4 | 1.1 | Yes |
| 62274 |  CHEMBL393055 | C20H34NO5P | 399.468 | 5 / 3 | 1.0 | Yes |
| 63879 |  CHEMBL194898 | C23H23N3O3 | 389.455 | 6 / 1 | 1.8 | Yes |
| 64301 |  CHEMBL209566 | C21H23N3O3 | 365.433 | 6 / 1 | 4.1 | Yes |
| 64835 |  CHEMBL378300 | C24H27N3O3 | 405.498 | 6 / 2 | 2.1 | Yes |
| 64839 |  CHEMBL378061 | C24H27N3O3 | 405.498 | 6 / 2 | 2.1 | Yes |
| 548655 |  CHEMBL3884862 | C20H22N2O2S | 354.468 | 5 / 3 | 1.2 | Yes |
| 523456 |  SCHEMBL3043580 | C17H25NO3 | 291.391 | 4 / 1 | 1.1 | Yes |
| 548662 |  CHEMBL3883572 | C24H23NO2S | 389.513 | 4 / 2 | 3.2 | Yes |
| 548672 |  CHEMBL3885415 | C25H23NO2S | 401.524 | 4 / 2 | 6.3 | No |
| 66378 |  FTY720P | C20H36NO5P | 401.484 | 6 / 4 | 1.1 | Yes |
| 69596 |  Sphingosine 1-phosphate | C18H38NO5P | 379.478 | 6 / 4 | 1.9 | Yes |
| 69616 |  AC1NQXRG | C18H38NO5P | 379.478 | 6 / 4 | 1.9 | Yes |
| 555755 |  SCHEMBL320988 | C24H24FNO4 | 409.457 | 6 / 1 | 1.7 | Yes |
| 523600 |  1-(4-phenethylbenzyl)azetidine-3-carboxylic acid | C19H21NO2 | 295.382 | 3 / 1 | 1.0 | Yes |
| 523615 |  SCHEMBL3034532 | C18H16F3NO2 | 335.326 | 6 / 1 | 1.3 | Yes |
| 70983 |  CHEMBL1951304 | C25H23N3O4S | 461.536 | 8 / 1 | 2.4 | Yes |
| 71442 |  CHEMBL210316 | C21H21BrN2O4 | 445.313 | 6 / 1 | 5.0 | Yes |
| 71767 |  CHEMBL247901 | C20H34NO5P | 399.468 | 6 / 4 | 1.1 | Yes |
| 71772 |  CHEMBL247698 | C20H34NO5P | 399.468 | 5 / 3 | 1.0 | Yes |
| 523669 |  SCHEMBL3044147 | C16H23NO3 | 277.364 | 4 / 1 | 0.4 | Yes |
| 548742 |  CHEMBL3883947 | C20H19NO4S | 369.435 | 6 / 2 | 1.4 | Yes |
| 548751 |  CHEMBL3885401 | C20H21NO2S | 339.453 | 4 / 2 | 1.9 | Yes |
| 75428 |  CHEMBL1779911 | C21H21NO2 | 319.404 | 2 / 1 | 5.3 | No |
| 75648 |  CHEMBL1824259 | C23H23NO | 329.443 | 1 / 1 | 4.9 | Yes |
| 78254 |  CHEMBL563746 | C20H31N2O5P | 410.451 | 7 / 3 | 1.1 | Yes |
| 548803 |  CHEMBL3885074 | C22H20N2O2S | 376.474 | 5 / 3 | 1.6 | Yes |
| 78547 |  CYM50260 | C14H11Cl3FNO2 | 350.595 | 4 / 0 | 4.9 | Yes |
| 80343 |  SR-02000000240 | C18H17NO2S | 311.399 | 3 / 1 | 4.6 | Yes |
| 555782 |  BDBM196221 | C23H22ClFN2O4 | 444.887 | 7 / 1 | 1.7 | Yes |
| 82000 |  CHEMBL389033 | C18H31N2O4P | 370.43 | 5 / 4 | 0.5 | Yes |
| 86105 |  SR-02000000249 | C22H15Cl2NO2 | 396.267 | 2 / 1 | 6.7 | No |
| 86244 |  CHEMBL589403 | C19H22N2 | 278.399 | 1 / 0 | 4.2 | Yes |
| 87508 |  CHEMBL601062 | C21H21N3O | 331.419 | 2 / 1 | 4.1 | Yes |
| 524070 |  SCHEMBL3043605 | C18H19NO2 | 281.355 | 3 / 1 | 0.8 | Yes |
| 89920 |  CHEMBL187645 | C20H42NO3P | 375.534 | 4 / 2 | 3.1 | Yes |
| 90807 |  VPC 23153, (R)-phosphoric acid mono-[2-amino-2-(6-octyl-1H-benzoimiazol-2-yl)-ethyl] ester, powder | C17H28N3O4P | 369.402 | 5 / 3 | 0.3 | Yes |
| 90812 |  CHEMBL361915 | C17H28N3O4P | 369.402 | 6 / 4 | 0.4 | Yes |
| 91116 |  CHEMBL603442 | C25H24N2O | 368.48 | 2 / 0 | 5.6 | No |
| 92687 |  CHEMBL380040 | C21H21N5O3 | 391.431 | 7 / 1 | 4.1 | Yes |
| 92757 |  CHEMBL210345 | C21H21N5O3 | 391.431 | 7 / 1 | 4.1 | Yes |
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