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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224599
Molecular formula	C23H19BrF3NO3S
IUPAC name	1-[[3-bromo-4-[[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Molecular weight	526.368
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.2
Synonyms	BDBM50158344 1-(3-bromo-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Inchi Key	BDXDATLHTUEDJA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H19BrF3NO3S/c24-19-8-14(10-28-11-16(12-28)22(29)30)6-7-20(19)31-13-17-9-18(15-4-2-1-3-5-15)21(32-17)23(25,26)27/h1-9,16H,10-13H2,(H,29,30)
PubChem CID	11466640
ChEMBL	CHEMBL224599
IUPHAR	N/A
BindingDB	50158344
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21319	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
21322	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
21320	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
21323	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
21321	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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