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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL364950
Molecular formula	C20H32N3O3PS
IUPAC name	1-dihydroxyphosphinothioyloxy-2-[5-(4-octylphenyl)-1H-imidazol-2-yl]propan-2-amine
Molecular weight	425.528
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	4.8
Synonyms	CHEMBL1184707 Thiophosphoric acid 2-amino-2-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-propyl ester; TFA BDBM50169453 SCHEMBL3925968
Inchi Key	BMWHKUCAPSSVAZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H32N3O3PS/c1-3-4-5-6-7-8-9-16-10-12-17(13-11-16)18-14-22-19(23-18)20(2,21)15-26-27(24,25)28/h10-14H,3-9,15,21H2,1-2H3,(H,22,23)(H2,24,25,28)
PubChem CID	44398012
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50169453
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27832	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
27830	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
27831	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
27833	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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