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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3359519
Molecular formula	C24H24F3NO4
IUPAC name	2-[6-[[4-propan-2-yloxy-3-(trifluoromethyl)phenyl]methoxy]-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid
Molecular weight	447.454
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.8
Synonyms	2-(7-(4-Isopropoxy-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acid BDBM50041980 SCHEMBL2017679 BCGUKCVQRODEEB-UHFFFAOYSA-N
Inchi Key	BCGUKCVQRODEEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24F3NO4/c1-14(2)32-22-6-3-15(9-19(22)24(25,26)27)13-31-18-4-5-20-17(10-18)11-21-16(12-23(29)30)7-8-28(20)21/h3-6,9-11,14,16H,7-8,12-13H2,1-2H3,(H,29,30)
PubChem CID	58329611
ChEMBL	CHEMBL3359519
IUPHAR	N/A
BindingDB	50041980
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442459	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
442461	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
442457	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
442460	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
442458	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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