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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224800
Molecular formula	C24H22F3NO4S
IUPAC name	1-[[3-methoxy-4-[[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Molecular weight	477.498
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	2.5
Synonyms	BDBM50158350 SCHEMBL13678358 1-(3-methoxy-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Inchi Key	CRSDAUWBRRWRFZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22F3NO4S/c1-31-21-9-15(11-28-12-17(13-28)23(29)30)7-8-20(21)32-14-18-10-19(16-5-3-2-4-6-16)22(33-18)24(25,26)27/h2-10,17H,11-14H2,1H3,(H,29,30)
PubChem CID	10310952
ChEMBL	CHEMBL224800
IUPHAR	N/A
BindingDB	50158350
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49055	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
49052	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
49056	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
49054	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
49053	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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