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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000570494
Molecular formula	C21H17BrFN3O2S
IUPAC name	4-[5-(4-bromophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide
Molecular weight	474.348
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.4
Synonyms	AKOS016068086 4-[3-(4-bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide CHEMBL1447076 SMR000186920 AC1MF1Z6 HMS3308A09 BDBM41685 MLS002539982 4-[5-(4-bromophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide cid_2864688 UNM-0000305850 AKOS002705834 MCULE-6373711058 4-[3-(4-bromophenyl)-5-(4-fluorophenyl)-2-pyrazolin-1-yl]benzenesulfonamide MolPort-000-207-686 HMS2164K23 [ Show all ]
Inchi Key	DQGIJMOOKDUPSB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H17BrFN3O2S/c22-16-5-1-14(2-6-16)20-13-21(15-3-7-17(23)8-4-15)26(25-20)18-9-11-19(12-10-18)29(24,27)28/h1-12,21H,13H2,(H2,24,27,28)
PubChem CID	2864688
ChEMBL	CHEMBL1447076
IUPHAR	N/A
BindingDB	41685
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66293	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
66290	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
66291	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
66292	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
66288	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
66289	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384

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