Detailed GPCR-I-TASSER Statistics for O95977

Submitted Sequence

>sp|O95977|S1PR4_HUMAN
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCSSSCCCCCSSSCCCCCCSSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 999999999765464322578874204467778878778997415999999999999998997686414421379889489999999999999999999999999960454447434332889999999999999999999708886046878755329999999999999999999999986050107987425344465404675448999999999999999999999987541463123888889989999999999999999999999996887677627999999999999999884999996499999999999477888877788987656556677788888887788877778888877778999986667879

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
Prediction 763443333253143234332332021210202424445324411100000100100210230130000000103300100000000001001101312110010003211200211010100011000100120000002000000010032332233100000000001101310310000001213342000011132100000002313321220020011001101310443644643331230010000001000000211200000000033230310010010010001100010000000105400300110000120325354454444444444444343544243464444446243445533444444647

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |    
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCSSSCCCCCSSSCCCCCCSSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
15tjvA 0.27 0.22 0.75 2.79Download -----------------------------ENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAGKRAMSF--SDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGK--MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF--------------------------------------------------------------
24z34A 0.33 0.28 0.79 3.70Download --------------NEPQCFYNESIAFFYNRSGKHLATEWNT--VSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQ-LHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFF---LLLAEFNSAMNPIIYSYRDKEMSATFRQIL--------------------------------------------------------------
35tgzA 0.26 0.24 0.76 3.20Download -------------------------GGRGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFP--HIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHA---PDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGK--MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF--------------------------------------------------------------
44z34 0.34 0.28 0.79 1.57Download --------------NEPQCFYNESIAFFYNRSGKHLATEWNT--VSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLERKAMYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQC-D-V-LAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG-------------------------------------------------------------
54ib4 0.17 0.17 0.75 1.18Download ---------------------------------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPPIKGIETNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADLEDLQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR---------------------------------------------------------
65tjvA 0.27 0.22 0.75 3.01Download -----------------------------ENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAG--KRAMSFSDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGK--MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF--------------------------------------------------------------
74z34 0.34 0.28 0.78 1.79Download -------------------FYNESIAFFYNRSGKHLATEW--NTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLERKAMYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDV---LAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG-------------------------------------------------------------
81u19A 0.20 0.22 0.86 4.58Download MNGTEGP---------------NFYVPFSNKTGVVRSPFEAPPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMALACAAPPLVGWSRYGMQ--CSCGIDYYTPHEETMFVVHFIIPLIVIFFCYGQLVFTVKEAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFG--PIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA-----------------------------------
95tjvA 0.27 0.22 0.75 2.95Download -----------------------------ENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAGKRAMSF--SDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKM--NKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF--------------------------------------------------------------
105g53A 0.23 0.21 0.73 2.92Download ---------------------------------------------SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS-TGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCCGEGQCLFEDVVPMNYMVYFNFFCVLVPLLLMLGVYLRIFLAARRQLKQM----TLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAP-LWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLENLY-----------------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-1.82 (Read more about C-score)
  • Estimated TM-score = 0.49±0.15
  • Estimated RMSD = 11.0±4.6Å

  • Download Model 2
  • C-score = -2.75

  • Download Model 3
  • C-score = -3.03

  • Download Model 4
  • C-score = -2.90

  • Download Model 5
  • C-score = -2.67


    • [Click on O95977_results.tar.bz2 to download the tarball file including all modeling results listed on this page]