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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000761483
Molecular formula	C20H19ClN2O
IUPAC name	7-[(2-chlorophenyl)-pyrrolidin-1-ylmethyl]quinolin-8-ol
Molecular weight	338.835
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.5
Synonyms	AC1NPY8G KSC-335-034 STL305051 7-[(2-chlorophenyl)-(1-pyrrolidinyl)methyl]-8-quinolinol BDBM64703 7-[(2-chlorophenyl)-pyrrolidino-methyl]quinolin-8-ol cid_5187118 SMR000371583 AKOS000807942 KUC112871N 7-[(2-chlorophenyl)-pyrrolidin-1-yl-methyl]quinolin-8-ol Oprea1_225050 7-[(2-chlorophenyl)pyrrolidinylmethyl]quinolin-8-ol HMS2681I13 ST50037288 7-[(2-chlorophenyl)(pyrrolidin-1-yl)methyl]quinolin-8-ol AKOS016290438 MCULE-5091568330 7-[(2-chlorophenyl)-pyrrolidin-1-ylmethyl]quinolin-8-ol CHEMBL1585527 Oprea1_813706 [ Show all ]
Inchi Key	AATWULBPEFPAGD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19ClN2O/c21-17-8-2-1-7-15(17)19(23-12-3-4-13-23)16-10-9-14-6-5-11-22-18(14)20(16)24/h1-2,5-11,19,24H,3-4,12-13H2
PubChem CID	5187118
ChEMBL	CHEMBL1585527
IUPHAR	N/A
BindingDB	64703
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
538	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
537	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
539	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
542	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
540	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
541	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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