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| Name | Apelin receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | APLNR |
| Synonym | msr/apj GPCR34 G-protein coupled receptor HG11 G-protein coupled receptor APJ AGTRL1 [ Show all ] |
| Disease | N/A |
| Length | 380 |
| Amino acid sequence | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVVD |
| UniProt | P35414 |
| Protein Data Bank | 5vbl |
| GPCR-HGmod model | P35414 |
| 3D structure model | This structure is from PDB ID 5vbl. |
| BioLiP | BL0380094, BL0380093 |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL1628481 |
| IUPHAR | 36 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 538 |  MLS000761483 | C20H19ClN2O | 338.835 | 3 / 1 | 4.5 | Yes |
| 968 |  MLS000389682 | C18H15ClN4O3 | 370.793 | 5 / 1 | 3.6 | Yes |
| 1744 |  CHEMBL2158341 | C15H11N3O5S | 345.329 | 9 / 0 | 1.5 | Yes |
| 2116 |  CHEMBL2158345 | C18H13N3O6S | 399.377 | 9 / 0 | 2.6 | Yes |
| 4915 |  MLS000681499 | C20H15N3O8 | 425.353 | 8 / 1 | 1.4 | Yes |
| 5328 |  3-(4-Nitro-benzyloxy)-7,8,9,10-tetrahydro-benzo[c]chromen-6-one | C20H17NO5 | 351.358 | 5 / 0 | 4.1 | Yes |
| 6044 |  MLS001206870 | C19H13NO7 | 367.313 | 7 / 0 | 3.8 | Yes |
| 6593 |  MLS000699844 | C17H14N2O5 | 326.308 | 5 / 0 | 2.8 | Yes |
| 7055 |  CHEMBL2158321 | C12H9FO3S | 252.259 | 5 / 1 | 2.1 | Yes |
| 7169 |  SMR000160170 | C13H22BrN5OS | 376.317 | 3 / 3 | 2.1 | Yes |
| 7742 |  CHEMBL3261785 | C52H89F3N16O12 | 1187.38 | 17 / 13 | -0.8 | No |
| 521671 |  CHEMBL3808736 | C73H117N25O17S2 | 1681.02 | 23 / 22 | -3.9 | No |
| 9025 |  MLS000860444 | C14H18N4OS | 290.385 | 5 / 2 | 4.0 | Yes |
| 9568 |  MLS000923770 | C20H18N2O7 | 398.371 | 7 / 1 | 1.8 | Yes |
| 10685 |  MLS000720075 | C13H9N5O5 | 315.245 | 7 / 1 | 1.8 | Yes |
| 11014 |  MLS001033014 | C14H17Cl2NO | 286.196 | 2 / 0 | 4.2 | Yes |
| 521825 |  CHEMBL3818742 | C24H24FN3O3 | 421.472 | 5 / 2 | 5.3 | No |
| 14078 |  MLS001239249 | C30H34N4O3S2 | 562.747 | 7 / 0 | 5.5 | No |
| 521888 |  CHEMBL3819352 | C25H28FN3O3 | 437.515 | 5 / 1 | 5.6 | No |
| 15021 |  MLS000528306 | C14H12N4S | 268.338 | 5 / 1 | 3.1 | Yes |
| 15100 |  disulfiram | C10H20N2S4 | 296.524 | 4 / 0 | 3.9 | Yes |
| 15503 |  MLS001239478 | C29H32N4O3S2 | 548.72 | 7 / 0 | 5.2 | No |
| 15840 |  (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene | C12H22O4S2 | 294.424 | 4 / 0 | 2.1 | Yes |
| 16891 |  beta-Escin | C55H86O24 | 1131.27 | 24 / 13 | 0.7 | No |
| 17617 |  MLS000039260 | C14H14N4O3 | 286.291 | 5 / 2 | 0.9 | Yes |
| 19082 |  CHEMBL2158335 | C18H16N2O5S2 | 404.455 | 8 / 0 | 2.9 | Yes |
| 20872 |  MLS002245453 | C23H26N2O8 | 458.467 | 8 / 1 | 4.0 | Yes |
| 20945 |  MLS001098424 | C12H12ClFN4O2S | 330.762 | 7 / 2 | 2.9 | Yes |
| 20961 |  MLS000723451 | C13H10N4O3 | 270.248 | 5 / 1 | 1.9 | Yes |
| 21090 |  MLS000520994 | C16H13N5O4S2 | 403.431 | 10 / 2 | 4.1 | Yes |
| 21982 |  MLS001196044 | C20H19NO3 | 321.376 | 4 / 1 | 4.4 | Yes |
| 22166 |  MLS000094900 | C25H26FN5O3S | 495.573 | 7 / 2 | 3.0 | Yes |
| 22569 |  BDBM46978 | C16H17NO4S | 319.375 | 5 / 2 | 4.5 | Yes |
| 25200 |  MLS001173828 | C15H14ClNO2 | 275.732 | 3 / 1 | 3.8 | Yes |
| 442673 |  CHEMBL3338694 | C82H127N13O16 | 1550.99 | 17 / 17 | 10.6 | No |
| 25598 |  CHEMBL2158271 | C19H15N3O8S | 445.402 | 11 / 0 | 2.1 | No |
| 522341 |  CHEMBL3818972 | C29H28FN3O5 | 517.557 | 7 / 2 | 5.1 | No |
| 558074 |  MLS000058898 | C13H22N2O2S | 270.391 | 4 / 1 | 3.3 | Yes |
| 27280 |  3,4,5-trimethoxy-N-[[phenyl(pyridin-2-yl)methylidene]amino]benzamide | C22H21N3O4 | 391.427 | 6 / 1 | 3.9 | Yes |
| 27348 |  CHEMBL3261767 | C55H96N22O13S | 1305.57 | 19 / 18 | -6.8 | No |
| 28058 |  SMR000103373 | C16H17NO | 239.318 | 2 / 0 | 3.8 | Yes |
| 28382 |  MLS000584397 | C19H20N2OS2 | 356.502 | 4 / 0 | 5.0 | Yes |
| 28559 |  MLS000698760 | C11H10ClN3S2 | 283.792 | 3 / 2 | 3.5 | Yes |
| 30567 |  MLS000679816 | C19H21N3O2S | 355.456 | 3 / 3 | 4.5 | Yes |
| 30587 |  MLS001116397 | C20H19ClN4O5S2 | 494.965 | 8 / 1 | 2.6 | Yes |
| 31205 |  4-chloro-N-(1-pyridin-2-ylethylideneamino)benzamide | C14H12ClN3O | 273.72 | 3 / 1 | 2.9 | Yes |
| 31558 |  MLS000564083 | C12H13Cl2N3O4 | 334.153 | 6 / 4 | 1.1 | Yes |
| 442925 |  CHEMBL3417386 | C72H112N22O16 | 1541.83 | 20 / 18 | -4.5 | No |
| 32752 |  MLS001219249 | C20H18N2O7 | 398.371 | 7 / 0 | 1.8 | Yes |
| 33000 |  CHEMBL2158355 | C21H20N2O5S | 412.46 | 8 / 0 | 3.6 | Yes |
| 34690 |  MLS000388665 | C23H18N4O2 | 382.423 | 3 / 2 | 4.3 | Yes |
| 35431 |  MLS000830367 | C24H28FN3O2 | 409.505 | 4 / 1 | 4.2 | Yes |
| 522605 |  CHEMBL3818936 | C19H22FN3O3 | 359.401 | 5 / 2 | 4.0 | Yes |
| 35891 |  2-(3-chloro-4-methylanilino)-1-phenylethanone | C15H14ClNO | 259.733 | 2 / 1 | 4.3 | Yes |
| 36260 |  MLS000568945 | C25H18N2O | 362.432 | 3 / 0 | 4.5 | Yes |
| 36774 |  MLS001174708 | C12H9Br2NOS | 375.078 | 3 / 1 | 5.0 | Yes |
| 443143 |  CHEMBL3338697 | C93H146N18O19 | 1820.3 | 20 / 21 | 9.2 | No |
| 36870 |  2-(3-propoxyphenyl)-N-(pyridin-2-ylmethylideneamino)quinoline-4-carboxamide | C25H22N4O2 | 410.477 | 5 / 1 | 4.9 | Yes |
| 38455 |  BDBM40988 | C23H25NO4S2 | 443.576 | 7 / 0 | 2.9 | Yes |
| 38532 |  MLS001239313 | C28H29FN4O3S2 | 552.683 | 8 / 0 | 4.9 | No |
| 38757 |  AC1MK6ZI | C18H17N3O6S | 403.409 | 7 / 3 | 3.2 | Yes |
| 38796 |  CHEMBL1557707 | C17H11N3O6S | 385.35 | 9 / 0 | 2.2 | Yes |
| 39018 |  MLS001157638 | C27H28N4O3 | 456.546 | 5 / 2 | 3.8 | Yes |
| 522725 |  CHEMBL3818625 | C27H30FN3O5 | 495.551 | 7 / 1 | 5.5 | No |
| 40664 |  MLS000438571 | C23H25NO4 | 379.456 | 5 / 0 | 4.2 | Yes |
| 522794 |  CHEMBL3819064 | C23H23FN4O6 | 470.457 | 8 / 3 | 2.0 | Yes |
| 43292 |  MLS000830852 | C16H17ClN2O | 288.775 | 2 / 2 | 4.9 | Yes |
| 44583 |  MLS000681503 | C15H12N2O5 | 300.27 | 6 / 0 | 2.3 | Yes |
| 47215 |  BDBM67234 | C19H17ClN2O4 | 372.805 | 5 / 2 | 3.5 | Yes |
| 47624 |  MLS002248991 | C22H17ClN4O8 | 500.848 | 9 / 1 | 2.7 | No |
| 522924 |  CHEMBL3817879 | C29H34FN3O5 | 523.605 | 7 / 2 | 6.2 | No |
| 48740 |  MLS000705563 | C13H11N3OS | 257.311 | 4 / 1 | 2.5 | Yes |
| 50180 |  MLS000568477 | C21H18BrN5O | 436.313 | 4 / 1 | 3.5 | Yes |
| 51004 |  MLS001165172 | C19H22N4 | 306.413 | 4 / 0 | 4.4 | Yes |
| 51443 |  CHEMBL2158005 | C17H10ClN3O6S | 419.792 | 9 / 0 | 2.8 | Yes |
| 51756 |  MLS000083273 | C23H30N6O4 | 454.531 | 7 / 0 | 1.7 | Yes |
| 53028 |  MLS001035334 | C19H18N2O7 | 386.36 | 7 / 0 | 1.9 | Yes |
| 53154 |  MLS000768883 | C16H13BrN2O7 | 425.191 | 7 / 1 | 3.1 | Yes |
| 54699 |  2-chloro-N-[[phenyl(pyridin-2-yl)methylidene]amino]benzamide | C19H14ClN3O | 335.791 | 3 / 1 | 4.6 | Yes |
| 55294 |  SMR000160396 | C21H18ClN3S2 | 411.966 | 5 / 0 | 4.8 | Yes |
| 55616 |  MLS000536984 | C21H18N2O6 | 394.383 | 7 / 0 | 4.0 | Yes |
| 56102 |  MLS000331887 | C11H12N6O2S | 292.317 | 6 / 2 | 2.0 | Yes |
| 56118 |  (4,6-diphenylpyrimidin-2-yl)hydrazine | C16H14N4 | 262.316 | 4 / 2 | 3.1 | Yes |
| 56523 |  Angustibalin | C17H20O5 | 304.342 | 5 / 0 | 2.0 | Yes |
| 56770 |  MLS000590711 | C22H20N4O4S | 436.486 | 6 / 3 | 4.0 | Yes |
| 57351 |  BAS 09669177 | C20H16N2O3S | 364.419 | 5 / 1 | 3.9 | Yes |
| 58598 |  SMR000045905 | C21H26N4O3 | 382.464 | 6 / 1 | 3.5 | Yes |
| 58676 |  MLS000438302 | C20H24O5 | 344.407 | 5 / 0 | 3.6 | Yes |
| 58757 |  CHEMBL2158342 | C18H12ClN3O8S | 465.817 | 10 / 0 | 2.0 | Yes |
| 59225 |  MLS000772464 | C13H7F2N3OS | 291.276 | 6 / 1 | 3.0 | Yes |
| 444032 |  CHEMBL3417376 | C66H110N22O16 | 1467.74 | 20 / 18 | -5.8 | No |
| 59547 |  CHEMBL2158261 | C21H20N2O4S | 396.461 | 7 / 0 | 4.0 | Yes |
| 60154 |  MLS000569070 | C18H11NO7 | 353.286 | 7 / 0 | 3.2 | Yes |
| 523301 |  CHEMBL3818163 | C25H20FN3O5 | 461.449 | 7 / 2 | 4.8 | Yes |
| 60927 |  CHEMBL1599381 | C22H21N3O6S2 | 487.545 | 10 / 0 | 2.4 | Yes |
| 61144 |  SMR000131240 | C21H31N3O3S | 405.557 | 5 / 1 | 3.7 | Yes |
| 523322 |  CHEMBL3290105 | C25H26FN3O5 | 467.497 | 7 / 2 | 4.4 | Yes |
| 61869 |  CHEMBL2158279 | C19H16N2O5S | 384.406 | 8 / 0 | 2.7 | Yes |
| 62095 |  MLS000770828 | C15H17ClN4O2S2 | 384.897 | 6 / 1 | 4.8 | Yes |
| 63060 |  AC1MEYUL | C21H17NO4 | 347.37 | 4 / 1 | 1.5 | Yes |
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