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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3290105
Molecular formula	C25H26FN3O5
IUPAC name	1-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
Molecular weight	467.497
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.4
Synonyms	BDBM50019423 SCHEMBL17114561
Inchi Key	DJDJKAVIQKSVPS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26FN3O5/c1-33-20-7-6-8-21(34-2)22(20)19-15-18(28-29(19)17-11-9-16(26)10-12-17)23(30)27-25(24(31)32)13-4-3-5-14-25/h6-12,15H,3-5,13-14H2,1-2H3,(H,27,30)(H,31,32)
PubChem CID	90644398
ChEMBL	CHEMBL3290105
IUPHAR	N/A
BindingDB	50019423
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
523322	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
61348	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
61347	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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