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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000705563
Molecular formula	C13H11N3OS
IUPAC name	6-ethyl-2-pyridin-2-yl-3H-thieno[2,3-d]pyrimidin-4-one
Molecular weight	257.311
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.5
Synonyms	6-ethyl-2-(2-pyridinyl)thieno[2,3-d]pyrimidin-4(3H)-one AR-434/42807715 Z55164162 6-ethyl-2-pyridin-2-yl-3H-thieno[2,3-d]pyrimidin-4-one AC1LGWBX HMS2521D08 6-ethyl-2-(2-pyridyl)-3H-thieno[2,3-d]pyrimidin-4-one BDBM67244 MolPort-002-849-341 ZINC8684349 CHEMBL1567827 6-ethyl-2-(2-pyridinyl)-3H-thieno[2,3-d]pyrimidin-4-one AKOS008024049 MCULE-3228650780 6-ethyl-2-(pyridin-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-4-one BRD-K69085837-001-11-0 SMR000232055 724745-45-3 cid_852940 [ Show all ]
Inchi Key	CREYUURVAPLCCE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H11N3OS/c1-2-8-7-9-12(17)15-11(16-13(9)18-8)10-5-3-4-6-14-10/h3-7H,2H2,1H3,(H,15,16,17)
PubChem CID	852940
ChEMBL	CHEMBL1567827
IUPHAR	N/A
BindingDB	67244
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48740	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
48741	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
48743	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
48742	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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