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Name | Apelin receptor |
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Species | Homo sapiens (Human) |
Gene | APLNR |
Synonym | msr/apj GPCR34 G-protein coupled receptor HG11 G-protein coupled receptor APJ AGTRL1 [ Show all ] |
Disease | N/A |
Length | 380 |
Amino acid sequence | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVVD |
UniProt | P35414 |
Protein Data Bank | 5vbl |
GPCR-HGmod model | P35414 |
3D structure model | This structure is from PDB ID 5vbl. |
BioLiP | BL0380094, BL0380093 |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1628481 |
IUPHAR | 36 |
DrugBank | N/A |
Name | 3-(4-Nitro-benzyloxy)-7,8,9,10-tetrahydro-benzo[c]chromen-6-one |
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Molecular formula | C20H17NO5 |
IUPAC name | 3-[(4-nitrophenyl)methoxy]-7,8,9,10-tetrahydrobenzo[c]chromen-6-one |
Molecular weight | 351.358 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 0 |
XlogP | 4.1 |
Synonyms | AC1LKSTW MCULE-7891071021 3-[(4-nitrophenyl)methoxy]-7,8,9,10-tetrahydrobenzo[c]chromen-6-one BAS 00872218 DTXSID40359761 [ Show all ] |
Inchi Key | AGYDNJPPEFCTLE-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H17NO5/c22-20-18-4-2-1-3-16(18)17-10-9-15(11-19(17)26-20)25-12-13-5-7-14(8-6-13)21(23)24/h5-11H,1-4,12H2 |
PubChem CID | 997475 |
ChEMBL | CHEMBL1490166 |
IUPHAR | N/A |
BindingDB | 76118 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <100000.0 nM | N/A | BindingDB |
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