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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001157638
Molecular formula	C27H28N4O3
IUPAC name	N-[4-[2-(diethylamino)ethylcarbamoyl]phenyl]-2-(furan-2-yl)quinoline-4-carboxamide
Molecular weight	456.546
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.8
Synonyms	AB00868641-06 N-[4-[2-(diethylamino)ethylcarbamoyl]phenyl]-2-(furan-2-yl)quinoline-4-carboxamide HMS2974H21 SMR000688507 AKOS007970086 MolPort-005-731-633 CHEMBL1313501 N-[4-[[2-(diethylamino)ethylamino]-oxomethyl]phenyl]-2-(2-furanyl)-4-quinolinecarboxamide MCULE-2800108959 ZINC12919415 BDBM76141 N-[4-[2-(diethylamino)ethylcarbamoyl]phenyl]-2-(2-furyl)cinchoninamide cid_24819417 NCGC00300854-01 [ Show all ]
Inchi Key	CCWOXRNCXQXGKI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N4O3/c1-3-31(4-2)16-15-28-26(32)19-11-13-20(14-12-19)29-27(33)22-18-24(25-10-7-17-34-25)30-23-9-6-5-8-21(22)23/h5-14,17-18H,3-4,15-16H2,1-2H3,(H,28,32)(H,29,33)
PubChem CID	24819417
ChEMBL	CHEMBL1313501
IUPHAR	N/A
BindingDB	76141
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39018	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
39017	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
39016	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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