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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000568945
Molecular formula	C25H18N2O
IUPAC name	2-[(2,4-diphenyl-6,7-dihydro-5H-chromen-8-yl)methylidene]propanedinitrile
Molecular weight	362.432
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.5
Synonyms	2-[(2,4-diphenyl-6,7-dihydro-5H-1-benzopyran-8-yl)methylidene]propanedinitrile CHEMBL1384372 ZINC4077496 MCULE-9340780067 BDBM67183 SMR000149964 2-[(2,4-diphenyl-6,7-dihydro-5H-chromen-8-yl)methylene]malononitrile cid_4244802 AC1N732K 101474-98-0 Z56760799 2-[(2,4-diphenyl-6,7-dihydro-5H-chromen-8-yl)methylidene]propanedinitrile HMS2487L08 AKOS001033733 MolPort-003-013-766 [ Show all ]
Inchi Key	BZAQGYIWMHOSTB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H18N2O/c26-16-18(17-27)14-21-12-7-13-22-23(19-8-3-1-4-9-19)15-24(28-25(21)22)20-10-5-2-6-11-20/h1-6,8-11,14-15H,7,12-13H2
PubChem CID	4244802
ChEMBL	CHEMBL1384372
IUPHAR	N/A
BindingDB	67183
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36260	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
36261	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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